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Studying a Type of Blood Test Used to Find Cancer in People With Sarcoma
The purpose of this study is to look at how well a special blood test called LP-WGS can find cancer in people with bone or soft tissue sarcoma (a type of cancer).
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Learning More about Immunotherapy Before and After Skin Cancer Surgery
The purpose of this study is to learn about a new way to treat skin cancer with surgery. We want to see if giving a type of medicine called immunotherapy before and after surgery helps people stay cancer-free longer than the usual treatment. We are trying to find out if this new way works better or worse than the regular way. We are looking for volunteers who have a kind of skin cancer called cutaneous squamous cell carcinoma that can be removed with surgery.
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Studying Two Medicines for Non-Small Cell Lung Cancer
The goal of this study is to learn how two medicines work together to treat non-small cell lung cancer. We want to find out if the medicines called amivantamab and Lazertinib are safe and helpful for people who have a certain change in a gene called EGFR.
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Studying the Medicine Sonrotoclax for Patients with Blood Cancer
The purpose of this study is to learn more about a new digital tool to help adolescents and young adult cancer survivors manage their symptoms of depression. People in the study will use the tool, answer questions, and join a video call. The goal is to find out if the tool helps them manage their feelings better. All study visits and consultations will be done virtually.
Study Topics
Mental Health Cancer Cancer: Children, Teens Children, Infants, Teen Health
Studying the Medicine Sonrotoclax for Patients with Blood Cancer
The purpose of this study is to learn more about a new medicine called sonrotoclax. We want to see if this medicine works better and is safe for people with a type of blood cancer called chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). We will compare the medicine to other approved treatments to see which one helps more. The goal is to help people feel better and live longer.
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Studying New Medicine and Chemo for Rare Throat Cancer
The purpose of this study is to find out if people are okay with taking physical and thinking tests before and after cancer treatment. The treatments, like chemotherapy and surgery, can change how your body works and how well you think. Some people get better faster than others, but we do not know why. By looking at your test results before and after treatment, the researchers can see how the treatment affected you.
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Studying New Medicine and Chemo for Rare Throat Cancer
The purpose of this study is to find out if people are okay with taking physical and thinking tests before and after cancer treatment. The treatments, like chemotherapy and surgery, can change how your body works and how well you think. Some people get better faster than others, but we do not know why. By looking at your test results before and after treatment, the researchers can see how the treatment affected you.
Study Topics
Cancer Cancer: Children, Teens Cancer: Ear, Nose, Mouth, Throat
Studying a New Medicine for a Rare Blood Cancer - Chronic Myeloid Leukemia (CML)
The purpose of this study is to learn more about a medicine for a rare blood cancer called chronic myeloid leukemia. We want to see if the medicine TERN-701 can safely stop or slow down cancer. This study is for patients with chronic myeloid leukemia (CML) who have already tried other treatments that did not work or caused problems.
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Studying New Treatments for Multiple Myeloma That Came Back
The purpose of this study is to find better ways to treat a type of cancer called multiple myeloma. We want to see if using different mixes of medicines works better than the usual treatment for people whose cancer came back or did not get better with other treatments. We also want to learn which medicines help the most, and check for any side effects to make sure the treatments are safe.
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Studying a New Vaccine for Infants and Toddlers
The purpose of this study is to learn about a new vaccine for healthy babies and toddlers. This vaccine is made to protect against a germ called pneumococcus, which can cause serious infections. The study will help researchers see how well the vaccine works and if it causes any side effects. We are looking for volunteers with a child who is 42 to 89 days old.
Study Topics
Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Treating Low-Risk, Early Stage Breast Cancer with Hormonal Therapy
The usual treatment for low-risk breast cancer is radiation and hormonal therapy. The purpose of this study is to find out how well hormonal therapy alone will work. We want to find out if this approach is better or worse than the usual approach.
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Comparing Two Medicines for CLL and SLL Blood Cancer
The purpose of this study is to see how two different medicines work for people with a type of blood cancer called CLL or SLL. We will compare how safe the medicines are and how well they help control the cancer. Our researchers hope to find out which medicine works better for people whose cancer has already been treated.
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Tracking the Long-Term Safety of the Medicine AGAMREE
Duchenne muscular dystrophy (DMD) is a disease that makes muscles get weaker over time. The purpose of this study is to track the long-term safety of a medicine called AGAMREE for this disease. People in the study will have yearly checkups and answer questions about their health. We are looking for volunteers who have DMD and are currently taking AGAMREE.
Study Topics
Genetic Disorders Men's Health Rare Disease Bones, Joints, Muscles Children, Infants, Teen Health
Studying the Medicine MK-2870 for Breast Cancer After Surgery
The purpose of this study is to learn more about a new medicine called MK-2870. We want to see if this medicine works better than current treatments for people with triple-negative breast cancer who had surgery but still have cancer. Our researchers want to see which treatment helps people live longer and feel better. They also want to learn about side effects and how safe the new medicine is.
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Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
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Studying the Medicine BMS-986482 for Advanced Solid Tumors
The purpose of this study is to learn more about the medicine BMS-986482. We want to see if this medicine is safe and works well for patients with certain types of cancer including non-small cell lung cancer, melanoma, colorectal cancer, breast cancer, urothelial cancer, prostate cancer, head and neck cancer or gastric cancer. We will compare this medicine alone or with other approved cancer medicines.
Study Topics
Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Head, Neck Cancer: Lung Cancer: Prostate Cancer: Skin Cancer: Stomach and Intestines Cancer: Urinary and Bladder
Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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A Study of the Drug Staccato Alprazolam for Patients with Prolonged Seizures
The purpose of this study is to learn more about the study drug Staccato Alprazolam. We want to see how well the study drug works for treating patients with previous episodes of prolonged seizures. We also want to learn more about the safety and side effects that may be caused by the study drug.
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