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Using Technology to Improve Care for Teens with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) affects the digestive system. Types of IBD include Ulcerative Colitis and Crohn's disease. The purpose of this study is to find out if text messaging can be used to help care for people with IBD. Volunteers must have a smartphone with text messaging.
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A Study of the Drug Efruxifermin for Patients with Liver Disease
The goal of this study is to find out if a drug called efruxifermin can help people with liver scarring caused by liver disease. We also want to know if the drug is safe and helpful for patients. Volunteers must have a liver disease where too much fat builds up, causing inflammation and scarring. Study team will provide more information.
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Electromagnetic Treatment for Stroke Recovery
The purpose of this study is to see if a wearable device helps stroke recovery. The device uses low-frequency electromagnetic fields to activate the brain. Volunteers must have had stroke onset 4 to 21 days ago.
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Learning More About the Long-Term Use of the Study Drug Staccato Alprazolam for Prolonged Seizures
The purpose of this study is to learn more about the long-term use of the study drug Staccato Alprazolam. We want to see how well the study drug works when used long-term for patients with a history of prolonged seizures. We also want to learn more about the safety and side effects that may be caused by the study drug.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Looking for Volunteers Interested in COVID-19 Related Studies
The purpose of this study is to make a list of people who want to volunteer for research and COVID-19 vaccine studies. This list is called the STRIVE registry. People on the list will be contacted about new studies they might join. Joining the list does not mean you have to join any future studies.
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Xeomin Injection for Stroke Recovery
The purpose of this study is to learn more about how the study drug, Xeomin, affects walking and balance after a stroke. We will use special devices to measure your movements. The study requires two visits to Carolinas Rehabilitation.
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Learning More About Using Sparsentan to Treat Glomerular Disease in Children
The purpose of this study is to find out how well the study drug, Sparsentan, works for treating kidney diseases in children. We also want to learn more about side effects that may be caused by the study drug.
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Comparing Two Study Drugs for Treatment of Vasculitis
Eosinophilic Granulomatosis with Polyangiitis is a disease that makes small blood vessels swell up in people with asthma. We want to see how two different study drugs, depemokimab and mepolizumab, work to treat this disease. We also want to learn about the possible side effects of each study drug.
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A Study of the Drug Batoclimab for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder. The purpose of this study is to learn more about the study drug Batoclimab. We want to see if this study drug is safe and helps people with CIDP.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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Learning More About Saliva and Dry Mouth
The purpose of this study is to find out what parts of saliva might cause people to feel like they have a dry mouth. By figuring this out, we can understand dry mouth better and treat it more effectively.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults?
This study is also known as PREVENTABLE, and the goal is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. This study is one of the largest research studies in adults aged 75 and older. Our researchers make it easy for people to join the study by connecting with them at home and sending the medication directly to their homes. They also check participants' health records and call them once a year to keep track of their progress. For more information, visit the PREVENTABLE website at www.preventabletrial.org or contact the study contact below.
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Improving the Care and Health of Children, Adolescents, and Young Adults with Inflammatory Bowel Disease
The purpose of this study is to improve the care and health for children, teens, and young adults with IBD (Inflammatory Bowel Disease). We want to gather information from your regular care visits to help improve the care for patients with inflammatory bowel disease. For example, we could learn which type of medication works best for treating this disease.
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Finding Signs of Hearing Problems in Babies with Cytomegalovirus Infection Present at Birth
The purpose of this study is to learn more about tests that can be used to show how a baby's hearing will be affected if they have cytomegalovirus (CMV) infection present at birth.
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Infectious Diseases Screening and Prevention Children, Infants, Teen Health Ears, Nose, Throat, Mouth
Studying a New Medicine for Kids and Teens with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a disease that makes muscles weak because the body's defense system attacks the spot where nerves and muscles connect. The purpose of this study is to learn more about a new medicine for kids and teens with this disease. Our researchers want to find out if the medicine is safe, how it works inside the body, and if it helps kids feel better and do everyday things more easily.
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Rare Disease Brain and Memory Children, Infants, Teen Health
New Treatment for ANCA Vasculitis in Kids and Teens
Active ANCA-associated Vasculitis is a disease where the body's immune system accidentally attacks its own small to medium-sized blood vessels. This makes the blood vessels swollen and damaged. The purpose of this study is to learn more about a treatment to help kids and teens with this disease. We want to see if the treatment called avacopan is safe and helpful.
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Rare Disease Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
A Study of the Drug ORIC-944 for Patients with Prostate Cancer
The purpose of this study is to learn more about the study drug ORIC-944. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has spread to other areas of the body.
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Studying New Treatments for High-Risk Head and Neck Cancer
The purpose of this study is to find a new treatment for people with head and neck cancer. We want to see if using radiation therapy with two different mixes of drugs is better than the usual treatment. The first mix is radiation therapy with the drugs called docetaxel and cetuximab. The second mix is radiation therapy with the drug called cisplatin and an immunotherapy drug called atezolizumab. We are looking for volunteers who have had surgery to remove high-risk cancer in the mouth, throat, voice box, or lower throat.
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