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High Blood Pressure in Children and Teenagers
The purpose of this study is to understand what causes high blood pressure in young people. We also want to learn more about how high blood pressure can cause damage to the heart and kidneys.
Study Topics
Healthy Volunteers Heart Health Children, Infants, Teen Health
Learning More about the Study Drug Lepodisiran to Reduce Heart Attacks and Stroke
The purpose of this study is to learn more about the study drug lepodisiran. We want to see if the study drug can reduce problems like heart attack or stroke in adults with elevated lipoprotein (a). We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Treating Atrial Fibrillation with Pulsed Field Ablation
The purpose of this study is to learn more about a new atrial fibrillation treatment called pulsed field ablation. We want to find out how well the treatment works.
Study Topics
Learning More About the Weight Loss Medication, Survodutide, and Risk of Heart Disease
The purpose of this study is to learn more about the study drug, Survodutide. We want to find out if the study drug can help overweight and obese patients lose weight without increasing the risk of heart disease.
Study Topics
How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
Study Topics
Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Learning More About Treating Severely High Triglyceride Levels with Pegozafermin
The purpose of this study is to see how well the study drug, Pegozafermin, helps with severely high triglyceride levels. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Using Inclisiran to Lower the Risk of Heart Attacks and Strokes in Adults with Heart Disease
The purpose of this study is to find out if the study drug, Inclisiran, can lower the risk of events like heart attacks and strokes. The study drug will be taken along with a medicine that can lower cholesterol. This study is being done at our High Point location.
Study Topics
A Study of the Drug Aficamten for Hypertrophic Cardiomyopathy
The purpose of this study is to learn more about the study drug aficamten for this condition. We want to learn more about the safety and tolerability of this drug.
Study Topics
A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
Study Topics
Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
Study Topics
Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
Study Topics
Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
Study Topics
Learning More About the Effects of Very Low-Nicotine Cigarettes on the Heart
The purpose of this study is to learn more about the effects of very low-nicotine cigarettes on the heart.
Study Topics
Heart Health Substance Use (Alcohol, Illegal Drugs, Tobacco)
Testing a New Home-Use Device for Detection of Irregular Heartbeats
The purpose of this study is to test a new home-use device called SANSA. We want to see if this device helps detect irregular heartbeats compared to the current tests already used by doctors. If successful, this device could help more people get diagnosed and treated for their irregular heartbeats.
Study Topics
Finding Out if Inclisiran Can Help Prevent Heart-Related Events Like Heart Attack or Stroke
The purpose of the study is to find out if the study drug, inclisiran, can prevent heart-related events by lowering LDL-cholesterol in the blood. LDL cholesterol is also known as bad cholesterol.
Study Topics
Testing a New Study Device for Mitral Valve Regurgitation
The purpose of this study is to test a study device called the CardioMech Mitral Valve Repair System for patients with this condition. We want to learn about the safety and effectiveness of this device.
Study Topics
Testing a New Heart Device for Patients with Heart Failure
The purpose of this study is to learn more about a study device called the OPTIMIZER Smart for patients with heart failure. We want to gather information on this device and see if it helps improve heart function and quality of life.
Study Topics
Treating Relapsing Multiple Sclerosis with BIIB091
The purpose of this study is to find out how well a new drug called BIIB091 works for treating relapsing multiple sclerosis. We also want to find out how well the body can handle taking the study drug.
Study Topics
Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics