Search Studies
Understanding Sleep Patterns Among Children and Young Adults with Cancer
The purpose of this study is to learn more about how sleep changes in children and young adults during and after cancer treatment. Our researchers want to understand when sleep problems start and how to treat them. The goal is to improve sleep and overall health during cancer care. We are looking for volunteers who were recently diagnosed with cancer and plan to receive cancer therapy.
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Studying a New Treatment for Virus After Transplant
Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV/PTLD) is a virus that can happen after receiving a solid organ transplant or allogenic cell transplant. The purpose of this study is to learn more about a new treatment called tabelecleucel. We want to see how well this treatment works for patients with this virus who did not get better with a treatment called rituximab or rituximab plus chemotherapy.
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Using MRI to Protect the Brain in Lung Cancer Patients
This study is about finding out if using brain scans alone, instead of brain scans plus preventive brain radiation, affects how long people with small cell lung cancer live.
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Studying What Concerns Care Teams about Immune Therapy for Transplants
The purpose of this study is to learn what makes doctors decide if they should use a certain cancer treatment in people who have had organ transplants and serious skin cancer. We will survey patients, doctors, and ethics experts (people who help others figure out what is right or wrong when making tough decisions). If you join the study, you will be asked to take a survey about your thoughts on a certain type of cancer treatment.
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Testing Different Treatment Doses for Newly Diagnosed Multiple Myeloma
Multiple myeloma is a type of cancer that starts in white blood cells. It is usually treated with drugs called isatuximab, lenalidomide, and dexamethasone. This study aims to test a lower dose of these drugs for people who are newly diagnosed with multiple myeloma. We want to see if the lower dose is safe and helpful.
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Studying a Mobile App for Heart Rehab Post-Valve Procedure
The purpose of this study is to find out if an at home mobile app can help improve heart health. The app is a heart rehab program and involves a health exercise program. Volunteers in the study will be put into one of three groups: no app, using the app for 12 weeks, or using the app for 24 weeks. We are looking for volunteers who have recently had, or will soon have, a heart valve procedure to fix their aortic, mitral, or tricuspid valve.
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Studying Radiation Plus Immune Therapy for Kidney Cancer
The purpose of this study is to see if adding radiation to immune therapy helps people with kidney cancer that has spread. We want to see if this new treatment keeps the cancer from getting worse longer than immune therapy alone. The goal is to find out which treatment works better. We are looking for volunteers with kidney cancer that has spread, and surgery is not currently recommended.
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Collecting Data on Patients with Cystic Fibrosis
The purpose of this study is to gather information on people with cystic fibrosis through a patient registry. The patient registry helps track important changes in people with cystic fibrosis. It also helps doctors understand the disease better, improve treatments, and help patients live longer.
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Genetic Disorders Lung Health Children, Infants, Teen Health
Using CTX001 to Treat Severe Sickle Cell Disease in Children
The purpose of this study is to learn more about using the study drug, CTX001, to treat sickle cell disease in children. We want to see how effective it is and if there are any side effects.
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Comparing Different Medication Combinations for Brain Artery Narrowing
The purpose of this study is to see how well the combination of study drugs, ticagrelor and aspirin or rivaroxaban and aspirin, help people who have had a stroke from narrowed brain artery. We want to see if the study drugs are better than the usual treatment in preventing another stroke or death.
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Collecting Data on Patients with Generalized Myasthenia Gravis
General Myasthenia Gravis is a rare disease that makes it hard for nerves and muscles to work together. This study collects information about people with this disease in a patient registry. The registry helps scientists learn new things that might help others in the future.
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Neurology Disorders Rare Disease Arthritis, Lupus, and Autoimmune Disorders
Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
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Comparing Treatments in Children Newly Diagnosed with Crohn's Disease
The purpose of this study is to learn more about why some children with Crohn's disease heal their bowel inflammation after one type of treatment and why others do not. Volunteers must have suspected Crohn's disease.
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Studying a Treatment for Patients with Severe Sjögren's Disease
Sjögren's disease is an autoimmune disorder that causes dry eyes and mouth. The purpose of this study is to learn about a new treatment for patients with this disease. We want to find out if the treatment, called nipocalimab, is safe and useful. To do this, we will compare the effects of nipocalimab to a placebo to see if it works.
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Testing a Device to Prevent Stroke in Patients with Patent Foramen Ovale
The purpose of this study is to test a new study device called the GORE CARDIOFORM Septal Occluder. We want to see if this device can help patients with this heart condition by closing the hole in the heart and preventing another stroke.
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Studying a New Treatment Plan for Patients with Large B-cell Lymphoma or Grade IIIB Follicular Lymphoma
We are looking for volunteers with Grade IIIB Follicular or Relapsed/Refractory Diffuse Large B-cell Lymphoma. The purpose of this study is to see if we can reduce the chance of your cancer growing or spreading by adding more treatment to the usual therapy. We are doing this study to see if this new approach is better or worse than the usual approach for patients who are getting CAR T-cell therapy.
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Studying Money Stress Among Patients with Leukemia
The purpose of this study is to see if helping people with money problems during cancer treatment can make them feel better and stay healthier. People in the study will answer questions about their health, feelings, and money. The goal is to find out if special help with money makes a difference.
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Studying the Drug Ipatasertib for Patients with Head and Neck Cancer
The purpose of this study is to learn more about the study drug Ipatasertib. We want to see if this study drug can be combined with chemotherapy and radiation for people with advanced head and neck cancer. The goal is to find the best dose of the drug and see if it is safe and useful.
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Testing a New Heart Device for Stroke Prevention
The purpose of this study is to test a new heart device called the Laminar System. We want to see if this device is safe and works well for people with a heart condition called non-valvular atrial fibrillation. The study will help doctors understand if this device can prevent strokes in these patients.
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Testing a New Heart Valve for Mitral Regurgitation
The purpose of this study is to test a new device called the AltaValve System. We want to see if it can help treat leaky heart valves. We want to find out if the device is safe and works well for people who cannot have open-heart surgery. The study is for adults with mitral valve regurgitation.
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