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Learning More About Muscle Mass and Cancer Treatment
The purpose of this study is to see if low muscle mass plays a role in the side effects from cancer treatment.
Study Topics
Treating Rectal Cancer with Irinotecan
This study is about testing a new way to treat advanced rectal cancer. The researchers want to see if adding the study drug, irinotecan, to the usual treatment will help more patients have their tumors disappear and stay cancer-free longer.
Study Topics
Using Cancer Cells in the Blood to Determine the Type of Chemotherapy that Will Benefit Colon Cancer Patients After Surgery
The purpose of this study is to help us learn more about using circulating tumor DNA (ctDNA) results to decide what chemo to offer patients after colon cancer surgery. ctDNA is DNA that has been released from tumor cells into your blood. Finding ctDNA in your blood means that there are likely small amounts of cancer after surgery. This study will help us find out if using ctDNA results to decide on treatment is better than the usual approach.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
Study Topics
Finding Out How Well Adding a Third Medication to Treatment Works for Treating Advanced Rectal Cancer
The purpose of this study is to find out if we can increase the likelihood of your tumor disappearing by adding a third drug to the usual treatment. We want to find out if this approach is better or worse than the usual approach.
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Study of the Drug AMG 355 in Patients with Advanced Solid Tumors
The purpose of this study is to learn more about the study drug AMG 355. We want to see how well the study drug works for treating advanced solid tumors. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Cancer Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Skin Cancer: Stomach and Intestines
Comparing Methods to Test for Anal Cancer and HPV
The purpose of this study is to compare three methods of collecting anal swabs for testing HPV and anal cancer. These methods include patients collecting swabs at home, patients collecting swabs in a clinic, and healthcare workers collecting swabs. The goal is to determine if all three methods provide the same results. We are looking for volunteers who are at high risk for anal cancer and meet the screening criteria for anal dysplasia.
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