Search Studies
Studying the Drug JNJ-90014496 for Patients with B Cell Non-Hodgkin Lymphoma
This study aims to learn more about the drug JNJ-90014496. We want to see if this drug is safe and helpful for treating patients with B cell Non-Hodgkin Lymphoma that has come back or hasn't responded to treatment.
Study Topics
A Study of the Drug AZD8205 for Treatment of Advanced Solid Tumors
The goal of this study is to learn more about the drug AZD8205 for treating serious tumors. We want to see if this drug is safe and if people can handle it well when used alone or with other cancer-fighting drugs. The study team will give more information about who can join the study.
Study Topics
A Study of the Drug OP-1250 for Advanced Breast Cancer Patients
The purpose of this study is to learn about the drug OP-1250 when used with either ribociclib or alpelisib. We want to see if this drug is safe and helpful for patients with advanced breast cancer or breast cancer that has spread, which is hormone receptor-positive and HER2-negative. We also want to find the best dose of this drug.
Study Topics
Treating Breast Cancer with a Combination of Drugs
The purpose of this study is to see how safe and effective the study drugs, trilaciclib, pembrolizumab, gemcitabine, and carboplatin, are in treating a type of cancer called Metastatic Triple-Negative Breast Cancer.
Study Topics
Testing the Study Drug Bromocriptine for New Moms with Heart Problems
Peripartum cardiomyopathy is when your heart gets weak and big during or after pregnancy. This makes it hard for your heart to pump blood like it should. The study is testing a drug called bromocriptine to help women with this problem.
Study Topics
Comparing Multi-day Versus Single Day Radiation Therapy for Brain Cancer
This study aims to find out if giving radiation over several days causes fewer side effects than giving it in one day for brain cancer patients on immunotherapy.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Breast Cancer: Kidney, Liver, Pancreas Cancer: Lung Cancer: Skin
Testing a New Drug System Called TAR-210 for Bladder Cancer
The purpose of this study is to learn more about a drug system called TAR210. We want to see if this drug system works better than regular bladder cancer. This study is for patients with a type of bladder cancer called Intermediate-Risk Non-Muscle-Invasive Bladder Cancer that has changes in a gene called FGFR.
Study Topics
Using a Small Device to Track Muscle Changes in ALS
Amyotrophic Lateral Sclerosis (ALS) is a disease that slowly makes muscles weaker and harder to control, making it tough to walk, talk, or breathe. The purpose of this study is to see how a small device called the mScan can measure muscle changes in people with ALS. The device uses a tiny, painless electrical signal to check muscles. Our researchers hope this will help track ALS over time and see how well treatments work.
Study Topics
Movement Disorder Neurology Disorders Rare Disease Bones, Joints, Muscles
Learning More about a New AML Cancer Treatment
The purpose of this study is to learn more about a cancer medicine called venetoclax. We want to see if adding this medicine to the usual chemotherapy can help treat patients with newly diagnosed myeloid leukemia (AML). We will compare this new treatment to the usual treatment for this type of cancer.
Study Topics
Comparing Two Medicines for Brain Cancer
The purpose of this study is to find out which medicine works better for people who have a type of brain cancer called glioblastoma. We will compare the medicine niraparib and temozolomide, along with radiation therapy. The goal is to see which treatment helps more and is safer.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers
Testing the Study Drug SNDX-5613 for Patients with Newly Diagnosed Acute Myeloid Leukemia
The purpose of this study is to learn more about the study drug SNDX-5613. We want to see if adding this study drug to the usual treatment can help patients who have just been diagnosed with a type of blood cancer called acute myeloid leukemia. We want to find out how much of the drug will cause serious side effects in patients. This will help doctors find out the best amount of the drug to use in future treatments for this cancer.
Study Topics
Studying the Medicine Remibrutinib for a Chronic Skin Condition
Hidradenitis suppurativa is a skin disease that causes painful lumps under the skin, often in areas like the armpits or groin. The purpose of this study is to see if the medicine remibrutinib can help adults with this disease. We want to see if the medicine can safely improve symptoms and improve overall health and well-being.
Study Topics
Studying the Medicine Bitopertin for Sun Sensitivity
Erythropoietic protoporphyria (EPP) or X-linked protoporphyria (XLP) are rare disorders that are passed down in families and cause a chemical to build up in the blood. This makes being in sunlight hurt their skin and can also affect their liver. The purpose of this study is to find out if a new medicine called bitopertin can help people with EPP or XLP stay in the sun longer without pain.
Study Topics
Studying a Lower Dose of Tamoxifen for Breast Cancer
The purpose of this study is to see if a lower dose of tamoxifen works as well as the regular dose to treat early-stage breast cancer. Tamoxifen is a medicine that helps stop cancer from coming back. Our researchers will also look at whether the lower dose causes fewer side effects for patients.
Study Topics
Studying a Rare Blood Condition Over Time
The purpose of this study is to learn more about a rare blood problem called plasminogen deficiency. Researchers will collect blood, urine, and health information to find out who gets symptoms and how to help them. The goal is to improve care for people with this condition.
Study Topics
Finding the Best Blood Cancer Treatment Using Blood Tests
The purpose of this study is to find out if doctors can quickly test blood and bone marrow to look for signs that help choose the best cancer treatment. These signs, called markers, can show which treatments might work best. If your test shows certain markers, you might be able to join a special treatment group. If not, your doctor will give you the usual care. We are looking for volunteers who have previously untreated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Study Topics
Studying Radiation vs Usual Care for Cancer that Spread to Bones
The purpose of this study is to help patients who have cancer that has spread to their bones but is not causing pain yet. We want to find out if giving radiation therapy before symptoms start can help prevent problems from bone cancer. Volunteers in this study will either get the usual care or the usual care plus radiation. The goal is to see which option works better to stop bone problems like fractures or spinal cord issues.
Study Topics
Cancer Cancer: Men's Cancer Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Solid Tumor Cancer: Women's Cancer
Helping the Brain Relax to Improve Sleep and Stress
The purpose of this study is to learn more about a new technology called Cereset Research (CR). It uses sounds linked to your brainwaves to help your brain relax and balance. In this study, you will continue your other current care, but will also receive sessions of CR. The goal is to see if it helps people with stress, anxiety, or trouble sleeping. We are looking for volunteers with symptoms following a concussion or traumatic brain injury (TBI), ongoing symptoms of long-COVID, or a functional movement disorder.
Study Topics
Studying the Medicine Dupilumab for Treating Rough, Itchy Skin
Lichen simplex chronicus (LSC), also called neurodermatitis, is a long-term skin condition that makes your skin very itchy and can cause thick, rough patches. The purpose of this study is to find out if a medicine called dupilumab can help adults who have this skin problem. Our researchers want to see if the medicine can make the itching better, help people sleep better, and improve how they feel about their health and daily life.
Study Topics
Studying Access to Food and its Impact on Blood Pressure
The purpose of this study is to learn more about access to food and blood pressure. Our researchers would like to explore different ways of helping people get better access to food and see if it can help improve their blood pressure. Some people will get help from a community health worker, and others may get meals made for people with high blood pressure. The goal is to find out which way works best. We are looking for volunteers who have high blood pressure and experience a lack of regular access to food.
Study Topics
Opinions, Social Issues Weight, Metabolism, Nutrition Wellness and Lifestyle Blood Pressure