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A Study of the Drug Deucravacitinib for Patients with Lupus
The purpose of this study is to learn more about the study drug Deucravacitinib. We want to see how well the study drug works for treating Lupus. We also want to learn more about the side effects that may be caused by the study drug.
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Comparing MitraClip and Surgery for Mitral Valve Repair
The purpose of this study is to test a study device called the MitraClipTM Device for patients with this condition and who are at moderate risk of surgery.
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Using the GORE® Device to Treat Heart Lesions
Aortic disease may cause wounds in the blood vessels near the heart. We want to learn more about the safety and how well the study device, GORE® Ascending Stent Graft, treats these wounds.
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A Study of the Drug Upadacitinib for Children with Ulcerative Colitis
The purpose of this study is to learn more about the study drug upadacitinib for treating ulcerative colitis, a type of bowel disease. We want to find out if the study drug is safe and works well for children with ulcerative colitis who have not had a response to other types of treatment.
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Testing a New Study Device for Severe Blood Flow Problems in Limbs
The purpose of this study is to learn more about speech profiles among stroke survivors and healthy volunteers. Understanding more about speech profiles can help customize treatment.
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Learning More About Speech Profiles after a Stroke
The purpose of this study is to learn more about speech profiles among stroke survivors and healthy volunteers. Understanding more about speech profiles can help customize treatment.
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Collecting Data for Parkinson's Disease Research
The purpose of this study is to gather information on people with Parkinson's disease through a patient registry. The registry will collect genetic information from people with Parkinson's, those at risk, and others without the disease. The registry will help improve understanding and care for Parkinson's disease.
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A Study of the Drug Valacyclovir for Babies at Risk of Herpes
The purpose of this study is to learn more about the study drug Valacyclovir. We want to figure out the best amount of the study drug that is needed for babies who may have been exposed to herpes when they were born.
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Testing the Study Device Impella for Patients with Severe Heart Disease
The purpose of this study is to learn more about the study device called Impella. We want to see if this device can be used during a high-risk heart procedure in patients with weak heart function on the left side. We want to learn if this device will improve symptoms and heart function after the procedure when compared to the standard of care treatment.
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Learning More About Dental Cleaning and Bacteria in the Bloodstream
The purpose of this study is to learn more about teeth cleaning and bacteria. We want to see if professional teeth cleaning and taking care of your teeth regularly will change the type of bacteria in the mouth. We also want to find out how often these bacteria get into your bloodstream when you brush your teeth.
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Testing a New Lung Cancer Risk Test
The purpose of this study is to test the Percepta Nasal Swab, a new nasal swab test for lung cancer risk. We want to see how useful this test is for determining lung cancer risk when a lung nodule is found during cancer screening.
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A Study of the Drug AZD5492 for Blood Cancer
The purpose of this study to learn more about the study drug AZD5492. We want to see if this study drug is safe and helpful for treating blood cancers that have not gotten better with other treatments. We need volunteers with certain types of blood cancer like B-cell non-Hodgkin's lymphoma or chronic lymphocytic leukemia/small lymphocytic lymphoma. The study team will provide more information.
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Testing the Study Drug CIN-102 for Diabetic Gastroparesis Treatment
Diabetic gastroparesis is a condition where the stomach takes too long to empty its contents. The purpose of this study is to learn more about the study drug CIN-102 for treatment of this condition. We want to test the safety and possible side effects of this study drug.
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Learning More About Using ABBV-383 to Treat Amyloidosis
The purpose of this study is to find out how safe and effective the study drug, ABBV-383, is in treating people with with amyloidosis.
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Learning More About Using Ivonescimab to Treat Lung Cancer
The purpose of this research study is to see if the study drug, ivonescimab, is safe and useful to treat people with a type of cancer called metastatic squamous non-small cell lung cancer.
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Studying a New Cancer Therapy for Advanced Solid Tumors
X-PACT is a new cancer treatment that uses a drug called psoralen and a low dose of X-rays. This study wants to see if this treatment is safe and helpful for patients. Volunteers need to have advanced head and neck cancer, soft tissue sarcoma, breast cancer, melanoma, or other solid tumors that didn't get better with other treatments.
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Testing a New Drug Combination for Patients with Myelofibrosis
The purpose of this study is to learn more about using two drugs called navtemadlin and ruxolitinib. We want to see if taking both drugs together helps treat patients with myelofibrosis. We also want to see if people can handle taking the drugs.
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Studying the Drug AZD7798 for Patients with Crohn's Disease
We are doing this study to find out if the study drug AZD7798 works well and is safe for treating Crohn's disease. We also want to learn more about Crohn's disease and the health problems it causes. AZD7798 targets a specific type of immune cell that we think might be causing inflammation in the gut for people with Crohn's disease.
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Using Ziftomenib to Treat Myeloid Leukemia
The purpose of this study is to see if the study drug, Ziftomenib, combined with other treatments is safe and useful to treat people with myeloid leukemia.
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Testing the Study Drug BCA101 for Advanced Solid Tumors
The goal of this study is to learn more about a drug called BCA101. We want to find out if this drug is safe and if it can help people with cancer that has come back or spread after treatment. This study is for volunteers who have solid tumors, like head and neck cancer, colorectal cancer, lung cancer, and other types. Study team will provide more information.
Study Topics