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Treating Ovarian Cancer with Avutometinib and Defactinib
The purpose of this study is to compare the combination of the study drugs, avutometinib and defactinib, to the usual treatment for a type of cancer called low grade serous ovarian cancer.
Study Topics
Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
Study Topics
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
Study Topics
Testing the Addition of chemotherapy to Hormonal Therapy for Breast Cancer
The purpose of this study is to compare two commonly used treatment choices for early-stage breast cancer in premenopausal women. We want to know if adding chemotherapy to hormonal therapy helps people with breast cancer.
Study Topics
Treating Vulvar Dysplasia with a New Surgical Treatment
This study is being done to see if a surgical treatment, Frozen-Section Directed Excision, is better at treating vulvar dysplasia than the usual treatment.
Study Topics
Using Selinexor to Treat Endometrial Carcinoma
The purpose of this study is to find out if the study drug, selinexor, is safe and effective for treating a type of cancer called endometrial carcinoma.
Study Topics
Study of Second Look Laparoscopy with Hyperthermic intraperitoneal chemotherapy (HIPEC) in Patients with Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
After their first surgery, patients often have a procedure called second look reassessment surgery. This surgery allows doctors to look inside your body and check for signs of cancer. The purpose of this study is to see how well it works to give HIPEC during the second look surgery. HIPEC is a type of chemotherapy inserted directly into your abdomen at the time of surgery. We want to monitor any effects that this has on your health.
Study Topics
Women's Health Cancer Cancer: Rare Cancers Cancer: Women's Cancer
Study Identifying Genetic Markers of Ovarian Cancer
The purpose of this study is to learn more about biological markers found in tissue, blood, and fluids. These markers may be able to tell us how severe a cancer can be and how well a cancer is responding to treatment.
Study Topics
Comparing Two Surgical Procedures to Reduce the Risk of Ovarian Cancer
The purpose of this study is to compare two different surgeries to reduce the risk of ovarian cancer. The study will look at the process used to decide which surgery is best for the patient. It will also look at symptoms that occur after removal of the ovaries.
Study Topics
Treating Low-grade Serous Ovarian or Peritoneal Cancer with Letrozole
The purpose of this study is to find out if we can we lower the chance of your ovarian or peritoneal cancer growing or spreading with the study drug Letrozole. We want to find out if this approach is better or worse than the usual approach for treating this type of cancer.
Study Topics
Cancer Cancer: Rare Cancers Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Women's Cancer