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Testing the Study Drug Bromocriptine for New Moms with Heart Problems
Peripartum cardiomyopathy is when your heart gets weak and big during or after pregnancy. This makes it hard for your heart to pump blood like it should. The study is testing a drug called bromocriptine to help women with this problem.
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Learning More About Using Ipatasertib to Treat Endometrial Cancer
The purpose of this study is to find out if adding the study drug, ipatasertib, to the usual treatment can help prevent cancer from growing or spreading.
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Testing Mosunetuzumab for Follicular Lymphoma
The purpose of this study is to learn more about the study drug Mosunetuzumab for patients with follicular lymphoma. We want to see if this study drug is better or worse than the usual treatment. We also want to learn about the sides effects of taking this drug.
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Testing a New Drug System Called TAR-210 for Bladder Cancer
The purpose of this study is to learn more about a drug system called TAR210. We want to see if this drug system works better than regular bladder cancer. This study is for patients with a type of bladder cancer called Intermediate-Risk Non-Muscle-Invasive Bladder Cancer that has changes in a gene called FGFR.
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Treating Rectal Cancer with Irinotecan
This study is about testing a new way to treat advanced rectal cancer. The researchers want to see if adding the study drug, irinotecan, to the usual treatment will help more patients have their tumors disappear and stay cancer-free longer.
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Comparing Multi-day Versus Single Day Radiation Therapy for Brain Cancer
This study aims to find out if giving radiation over several days causes fewer side effects than giving it in one day for brain cancer patients on immunotherapy.
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Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Breast Cancer: Kidney, Liver, Pancreas Cancer: Lung Cancer: Skin
Learning More about a New AML Cancer Treatment
The purpose of this study is to learn more about a cancer medicine called venetoclax. We want to see if adding this medicine to the usual chemotherapy can help treat patients with newly diagnosed myeloid leukemia (AML). We will compare this new treatment to the usual treatment for this type of cancer.
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Finding the Best Blood Cancer Treatment Using Blood Tests
The purpose of this study is to find out if doctors can quickly test blood and bone marrow to look for signs that help choose the best cancer treatment. These signs, called markers, can show which treatments might work best. If your test shows certain markers, you might be able to join a special treatment group. If not, your doctor will give you the usual care. We are looking for volunteers who have previously untreated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Studying the Drug VX-670 for Adults with Myotonic Dystrophy Type 1
The purpose of this study is to learn more about the study drug VX-670. We want to find out if it is safe and if adults with myotonic dystrophy type 1 can handle it well.
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Testing a New Formula of Cladribine for Patients with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a condition where the body's defense system attacks the muscles, making them weak and tired. The purpose of this study is to find out how well a new medicine called Cladribine works compared to a fake medicine. We also want to see how well patients can handle the new medicine.
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Testing if Oxytocin Helps You Feel Less Heat Pain After a Mild Sunburn
The purpose of this study is to see how oxytocin affects your ability to feel touch and heat. They will give you oxytocin through an IV (a tube in your vein). They will test this on normal skin and on skin that has a mild sunburn from UV-B light. In this study, you will either get oxytocin or a placebo (a fake solution that doesn't do anything).
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Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
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A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
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Testing Spinal Cord Stimulation for Stiffness and Pain in Stiff Person Syndrome
Stiff person syndrome is a rare disease that makes your muscles very stiff and can cause painful muscle spasms. This study wants to find out if using spinal cord stimulation can help make these symptoms better.
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Studying the Safety of the Flu Vaccine and COVID-19 Vaccine Among Pregnant People
The purpose of this study is to find out if it is safe for pregnant people to get the flu and COVID-19 vaccines together. We will compare getting both shots on the same day or 7-14 days apart.
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A Study of the Drug LBP-EC01 for the Treatment of Urinary Tract Infections
The goal of this study is to learn more about the drug LBP-EC01. We want to see if it is safe and helpful for treating females with frequent or recurrent urinary tract infection (UTI) caused by a bacteria called E. coli but particularly E. coli that is resistant to at least one antibiotic.
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Studying the Drug MT-7117 for Patients with a Rare Blood Disorder
The purpose of this study is to learn more about the study drug MT-7117. We want to see if this study drug is useful for patients with a rare blood disorder called Erythropoietic Protoporphyria. We also want to see if this study drug is tolerable to take.
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Testing the Study Drug Levocarnitine to Prevent Liver Damage in Leukemia or Lymphoma Patients
The purpose of this study to learn more about the study drug Levocarnitine. We want to see if this study drug protects the liver from chemotherapy for leukemia or lymphoma.
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Studying the Drug Plozasiran for Patients with Severe Hypertriglyceridemia
Hypertriglyceridemia is when you have too much fat in your blood. This study wants to see if the drug plozasiran is safe and works well to lower this fat in people with severe hypertriglyceridemia.
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