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Can Exact MRD Detect the Return of Cancer Earlier than the Usual Testing
The purpose of this study is to see how well the study test detects if cancer has come back after surgery. The study test may be able to detect very small amounts of cancer in the blood.
Study Topics
Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Adding the Study Drug Apalutamide to the Usual Treatment for Prostate Cancer After Surgery
The purpose of this study is to find out if we can extend the time without your prostate cancer spreading by adding the study drug to the usual treatment. We want to find out if this approach is better or worse than the usual approach for your prostate cancer.
Study Topics
IGROOVE: A Dance and Music Study for Older Adults with Memory Concerns
The purpose of the study is to see how music and dance may affect fitness and brain health. The study will include people who are concerned about their memory but have not been diagnosed with memory loss.
Study Topics
Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
Study Topics
Looking Into the Need of Blood Thinners as Treatment for Atrial Fibrillation
Blood thinning drugs are usually used to treat atrial fibrillation. Atrial fibrillation is when the heart has an irregular and often very fast heart rhythm. Blood thinners lower the risk of stroke but also increase the risk of bleeding. It may not be necessary for people who have short or infrequent atrial fibrillation to take blood thinners. The purpose of this study is to find out if it is safe to stop blood-thinning medication during long periods of normal heart rhythm.
Study Topics
Looking for Volunteers Interested in COVID-19 Related Studies
The purpose of this study is to make a list of people who want to volunteer for research and COVID-19 vaccine studies. This list is called the STRIVE registry. People on the list will be contacted about new studies they might join. Joining the list does not mean you have to join any future studies.
Study Topics
Treating Early Stage HER2-Positive Breast Cancer Without Radiation Therapy
The usual treatment for early stage HER2-positive breast cancer is HER2-targeted therapy and radiation therapy. The purpose of this study is to see how well treatment without radiation therapy works. We want to find out which approach is better.
Study Topics
Finding Out How Well the Study Drug, HU6, Works for Treating Patients with Obesity and Heart Failure
The purpose of this study is to learn more about the study drug, HU6. The study will help us find out how the study drug affects weight loss and the ability to exercise. It will also help us see what side effects may be caused by the study drug.
Study Topics
Comparing Different Medication Combinations for Brain Artery Narrowing
The purpose of this study is to see how well the combination of study drugs, ticagrelor and aspirin or rivaroxaban and aspirin, help people who have had a stroke from narrowed brain artery. We want to see if the study drugs are better than the usual treatment in preventing another stroke or death.
Study Topics
Can Physical Activity Be Helpful for Lymphoma Patients During Treatment
The purpose of this study is to find out if exercise or educational classes can be helpful for lymphoma patients. We want to know if exercise or classes can help patients keep their quality of life and ability to exercise. We also want to know if exercise or classes can help lymphoma patients with memory and heart health.
Study Topics
Testing the Study Drug STP0404 for Treatment of HIV-1
The purpose of this study is to find out if the study drug, STP0404, decreases the amount of HIV virus in your body. We also want to learn more about the possible side effects of the study drug.
Study Topics
Collecting Data on Patients with Generalized Myasthenia Gravis
General Myasthenia Gravis is a rare disease that makes it hard for nerves and muscles to work together. This study collects information about people with this disease in a patient registry. The registry helps scientists learn new things that might help others in the future.
Study Topics
Neurology Disorders Rare Disease Arthritis, Lupus, and Autoimmune Disorders
Using Dexpramipexole for the Treatment of Severe Eosinophilic Asthma
The purpose of this study is to find out how well the study drug dexpramipexole works for the treatment of severe asthma. We also want to learn more about the safety of the study drug.
Study Topics
Learning More About How Patients Take Their Psoriasis Medication
The purpose of this study is to learn more about how people choose to take their psoriasis medication. We want to find out if sending daily and weekly reminders will help patients take their medication as directed. The study will also look at how well the medication works for patients who take it as directed compared to those who do not. Taking part in this study involves two office visits, taking a daily med, and an exit interview.
Study Topics
Comparing Treatments in Children Newly Diagnosed with Crohn's Disease
The purpose of this study is to learn more about why some children with Crohn's disease heal their bowel inflammation after one type of treatment and why others do not. Volunteers must have suspected Crohn's disease.
Study Topics
Treating Glioblastoma with the Study Drug Dichloroacetate
The purpose of the study is to find out if the study drug, Dichloroacetate, can keep glioblastomas from growing. We want to know if the study drug can help improve the health of patients with glioblastomas that have returned or been difficult to treat.
Study Topics
Early Chronic Obstructive Pulmonary Disease (COPD) in Younger Patients
Chronic obstructive pulmonary disease (COPD) is a lung disease that causes blocked airflow from the lungs. The purpose of this study is to learn more about COPD in younger people that are at risk.
Study Topics
Collecting Samples for Cancer Screening
The purpose of this study is to collect blood samples to help create a cancer screening test. The screening test aims to find many different types of cancers including lung, colorectal, ovarian, pancreatic, liver, bladder, stomach and esophageal cancers.
Study Topics