Search Studies
Studying Plixorafenib for Cancers with BRAF Gene Changes
The purpose of this study is to learn more about the medicine plixorafenib. We want to see if this medicine can help people whose cancer has a change in the BRAF gene. The medicine is being studied to see if it works and if it is safe. People in the study will take the medicine and be watched closely for any changes or side effects.
Study Topics
Studying a New Medicine to Help People with Type 2 Diabetes Lose Weight
The purpose of this study is to see if a new medicine can help people with type 2 diabetes who are overweight or obese lose weight safely. Our researchers will compare the new medicine to a placebo to see how well it works and if it is safe. Volunteers in the study will get regular check-ups and tests to make sure they stay healthy.
Study Topics
Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
Study Topics
Testing Spinal Cord Stimulation for Stiffness and Pain in Stiff Person Syndrome
Stiff person syndrome is a rare disease that makes your muscles very stiff and can cause painful muscle spasms. This study wants to find out if using spinal cord stimulation can help make these symptoms better.
Study Topics
A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
Study Topics
Exploring a New Program to Care for Rural Patients with Chronic Pain
The purpose of this study is to test a new program for patients in rural areas with chronic pain. We want to see if this program can help patients better manage their pain and daily functioning by working with a nurse care manager.
Study Topics
Testing the Study Drug Levocarnitine to Prevent Liver Damage in Leukemia or Lymphoma Patients
The purpose of this study to learn more about the study drug Levocarnitine. We want to see if this study drug protects the liver from chemotherapy for leukemia or lymphoma.
Study Topics
Studying the Drug MT-7117 for Patients with a Rare Blood Disorder
The purpose of this study is to learn more about the study drug MT-7117. We want to see if this study drug is useful for patients with a rare blood disorder called Erythropoietic Protoporphyria. We also want to see if this study drug is tolerable to take.
Study Topics
Testing the Study Drug Lutikizumab for Severe Skin Disease
Hidradenitis suppurativa is a skin problem that causes painful bumps and boils under the skin. The purpose of this study is to find out if the study drug lutikizumab is safe and useful for treating this skin problem.
Study Topics
Testing the Study Drug DFP-10917 for Patients with Acute Myeloid Leukemia
The purpose of this study is to find out more about the drug DFP-10917. We want to see if it is safe and helpful for treating people with acute myeloid leukemia.
Study Topics
Testing a New Study Device for Brain Aneurysms
A saccular intracranial aneurysm is a balloon-like bump in a brain blood vessel that can burst and cause big problems. The purpose of this study is to see if a new device is safe and helpful for treating this condition.
Study Topics
Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
Study Topics
Studying the Medicine Apitegromab for Babies with Muscle Weakness
Spinal muscular atrophy is a disease that makes muscles weak and hard to move. The purpose of this study is to test a new medicine called apitegromab. We want to see if it is safe and helpful for babies under 2 years old who still have trouble moving even though they already got another treatment called survival motor neuron therapy.
Study Topics
Genetic Disorders Movement Disorder Neurology Disorders Rare Disease Bones, Joints, Muscles Children, Infants, Teen Health
Studying the Medicine Apitegromab for Babies with Muscle Weakness
The purpose of this study is to see if a blood test can help doctors decide who needs extra cancer treatment after surgery for bladder, kidney. Ureter, or urethra cancer. The blood test looks for cancer DNA in the blood. If the test finds cancer DNA, patients may get one or two cancer drugs, or they may be watched closely.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Urinary and Bladder
Studying New Glucose Sensors for People with Diabetes
The purpose of this study is to see how well new glucose sensors work. These sensors help people with diabetes track their blood sugar. The study compares the new sensors to ones already sold in stores.
Study Topics
Learning the Best Ways to Treat Broken Bones and Reduce Future Fractures
The purpose of this study is to learn more about different ways to care for patients after they break a bone and to reduce your chances of having another fracture. We are looking for volunteers with a recent bone break and who have a regular doctor. They also must not have certain health conditions like cancer, severe kidney disease, or other bone diseases. The study team will provide more information.
Study Topics
Managing Osteoarthritis Pain with Movement and Healthy Eating at Home
Osteoarthritis is a condition that causes pain and stiffness in the joints, often in the hips and knees. The purpose of this study is to find ways to help people with chronic pain due to this condition. We want to find a drug-free way to better manage symptoms through movement and healthy eating. The study is done entirely at home with virtual visits and assessments. The study team will provide more details.
Study Topics
Pain Arthritis, Lupus, and Autoimmune Disorders Weight, Metabolism, Nutrition Bones, Joints, Muscles
Comparing Different Migraine Medicines
The purpose of this study is to learn more about three migraine medicines: atogepant, propranolol, and topiramate. Our researchers want to see which one helps prevent migraines the best. Volunteers in the study will try one medicine and keep track of their headaches. The results will help doctors and patients choose the best medicine for migraine prevention.
Study Topics
Helping People with HIV Quit Smoking Using Apps
The purpose of this study is to learn more about two different ways to help people with HIV quit smoking. The first way is to use the app called QuitStart along with the use of nicotine gum and patches. The second way is to use the app called Learn to Quit-HIV (LTQ-H) along with the use of nicotine gum and patches. We will compare each way to understand the pros and cons of each approach. We are looking for volunteers who have HIV and have smoked cigarettes every day in the past 30 days.
Study Topics
HIV/AIDS Substance Use (Alcohol, Illegal Drugs, Tobacco) Wellness and Lifestyle
Studying Hair Loss and Family History
The purpose of this study is to learn more about what might cause a kind of hair loss called Frontal Fibrosing Alopecia. We are looking for Black or African American women who have this condition. If you join the study, you will be asked to answer a short survey, have pictures taken of your scalp, and give a saliva sample so we can look at your DNA. We are also looking for family members-whether they have hair loss or not-to take part. This is not a treatment study.
Study Topics