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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults?
This study is also known as PREVENTABLE, and the goal is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. This study is one of the largest research studies in adults aged 75 and older. Our researchers make it easy for people to join the study by connecting with them at home and sending the medication directly to their homes. They also check participants' health records and call them once a year to keep track of their progress. For more information, visit the PREVENTABLE website at www.preventabletrial.org or contact the study contact below.
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Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
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Learning More About Brain Health and Alzheimer's Disease
The purpose of this study is to learn more about brain health and the full spectrum of Alzheimer's disease from its earliest stages. This is an observational research study, which means it has no study drug or treatment.
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How Damage to Blood Vessels in the Brain May Be Related to Thinking and Memory Problems Like Dementia
This study is being done to better understand how damaged blood vessels affect your thinking. This is not a treatment study.
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Taking Dasatinib and Quercetin Together to Help Slow the Progression of Alzheimer's (SToMP-AD Study)
The purpose of this study is to see how well a combination of meds may treat early Alzheimer's disease. The meds dasatinib and quercetin will be taken together.
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Can Metformin Help with Decline in Memory?
The purpose of this study is to see how well the medicine Metformin can help patients with memory decline.
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Effects of a Low-Carbohydrate and Low-Fat Diet in Adults with Mild Memory Loss (BEAT-AD Study)
The purpose of this study is to look at the effects of a low-carbohydrate diet and low-fat diet in adults with mild memory loss. We want to see if changes in diet can improve memory.
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Studying New Ways to Reduce Caregiver Stress
The purpose of this study is to see if listening to nature sounds and using a new technology called CR can help people who take care of loved ones feel less stressed. Taking care of someone can be stressful and affect your health. This study will test if CR can help reduce stress symptoms like anxiety, trouble sleeping, and changes in heart rate in a small group of people.
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Healthy Volunteers Mental Health Neurology Disorders Sleep Brain and Memory
Improving Memory by Improving Sleep
Sleep is a critical part of long-term memory storage. Aging can cause issues with sleep and memory. The goal of this study is to see if improving sleep can improve memory. Volunteers will wear a headband during sleep that will record brain activity. This headband will also provide low-level electrical stimulation to increase deep sleep. Deep sleep is a stage of sleep that is important for memory.
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Finding Out How Well Rimegepant Works for Treating Migraines in People Ages 12 to 17
The purpose of this study is to find out how well the study drug, Rimegepant, works for treating migraines in people age 12 to 17. We also want to find out how safe it is in children and young people.
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Neurology Disorders Pain Brain and Memory Children, Infants, Teen Health
How Myotonic Dystrophy Type 2 Affects the Brain
Myotonic dystrophy affects the muscles and other body systems. The purpose of this study is to look at the impact myotonic dystrophy type 2 has on the brain. We also want to look at brain-based symptoms like problems with thinking, memory or motivation.
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Head Trauma Among Student Athletes
We want to learn about how head movement during a contact sport-related hit to the head affects the brain. Contact sports include those which may involve contact to the head during play such as football and soccer.
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Healthy Volunteers Brain and Memory Children, Infants, Teen Health
Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults
This purpose of this study is to find out if a drug called atorvastatin can help older adults live well for longer by preventing dementia, disability or heart disease.
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IGROOVE: A Dance and Music Study for Older Adults with Memory Concerns
The purpose of the study is to see how music and dance may affect fitness and brain health. The study will include people who are concerned about their memory but have not been diagnosed with memory loss.
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Treating Early Alzheimer's Disease with the Study Drug CT1812
The purpose of this study is to find out if the study drug, CT1812, can slow memory decline. We want to see how well it works for people with mild memory decline due to Alzheimer's disease and dementia.
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Study of Memory Loss in the African-American Population
The purpose of this study is to better understand what causes memory loss in African Americans. We hope this type of research will result in improved diagnosis, better treatment and possibly prevention.
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How Brain Activity Relates to Your Ability to Shift Attention in Response to Images
The purpose of this study is to look at how brain activity is related to your ability to shift attention when visual cues change. You will be asked to view specified images while receiving an MRI scan.
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Comparing the Drugs Aspirin and Apixaban to See How Well They Work at Preventing Stroke or Death
The purpose of this study is to look at the how the drugs apixaban and aspirin effect patients with irregular heartbeat and recent brain bleeding. We also want to find out which is better at preventing future strokes and death.
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Studying the Long-Term Usefulness of a Parkinson's Disease Treatment
The purpose of this study is to see how well the drug ABBV-951 works for people with advanced Parkinson's Disease over a long time. We will look at how the drug affects movement, daily activities, and changes in the disease over three years. We need volunteers who have never taken the drug before or who have used it before. The study team will give more details.
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Using Imaging to Understand Brain Activity at Rest
The goal of this study is to learn about how the brain works when you are resting. We will use a special brain scan called magnetoencephalography to see what happens in the brain when you are sitting still and relaxed. Findings from this study will help us use this brain scan better in future research.
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