Search Studies
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
Study Topics
Studying Treatment Options for Multiple Myeloma After a Stem Cell Transplant
The purpose of this study is to find out which treatment works best to keep multiple myeloma from coming back after a stem cell transplant. Our researchers will compare three options: a new medicine called teclistamab with standard treatment called lenalidomide, lenalidomide alone, or teclistamab alone. The goal is to see which treatment helps people stay healthy longer.
Study Topics
Studying Ablative Local Therapy for Colorectal Cancer
The purpose of this study is to learn if adding special tumor treatments, called ablative local therapy, can help people with colorectal cancer that has spread. These treatments may use surgery, radiation, or heat to target all tumor spots. The goal is to see if adding these treatments to usual cancer medicine helps people live longer.
Study Topics
Studying a New Medicine for Generalized Myasthenia Gravis
Acetylcholine receptor antibody positive generalized myasthenia gravis (AChR+ gMG) is a disease where the body's immune system attacks the places where nerves talk to muscles, making the muscles weak and tired. The purpose of the study is to learn more about a new medicine and see how well it helps people in their everyday activities.
Study Topics
Neurology Disorders Rare Disease Arthritis, Lupus, and Autoimmune Disorders
Helping Improve Breast Cancer Care for Young Women
The purpose of this study is to learn more about breast cancer in younger women and help improve care in the future. Researchers will collect blood, tissue, and stool samples from women who were diagnosed with breast cancer between the ages of 18 and 45. They will look for patterns and differences to help guide future research and treatment.
Study Topics
Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
Study Topics
Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
Study Topics
Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)
Studying a Medicine for Babies with Alagille Syndrome
The purpose of this study is to learn more about a medicine called Odevixibat for babies with Alagille Syndrome. We want to see if this medicine can safely help reduce itching in babies with this health condition.
Study Topics
Genetic Disorders Rare Disease Children, Infants, Teen Health
Studying the Drug SNDX-5613 for Patients with Acute Myeloid Leukemia
The study aims to learn more about the drug SNDX-5613. We want to find the best dose for patients with a blood cancer called acute myeloid leukemia. We also want to see how this drug works when used with two other drugs, daunorubicin and cytarabine.
Study Topics
Studying Blood Particles to Help Treat Cancer
The purpose of this study is to learn more about tiny particles in the blood called extracellular vesicles. By studying this, we hope to find out more about different types of cancer and how to treat them better. We will look at the blood samples from patients with similar cancers to see if we can discover new information. This could help doctors choose the best treatments for cancer patients in the future. We are looking for volunteers with urothelial, prostate, or kidney cancer. The study team will provide more information.
Study Topics
Studying Repotrectinib for Treating Solid Tumors in Children and Young Adults
The purpose of this study is to learn more about a new cancer medication called repotrectinib for children and young adults. We want to see if this medication can safely treat patients with a solid tumor that has spread from the original tumor site to the area around it or to other parts of the body. The study team will provide more information.
Study Topics
Using Levocarnitine to Protect the Liver During Chemotherapy
The study aims to find out if the study drug, levocarnitine, can reduce severe liver damage caused by chemotherapy in patients with certain cancers.
Study Topics
Kidneys, Liver, Pancreas Cancer Cancer: Leukemia Cancer: Lymphoma
Studying a New Blood Test for Patients with Blood Cancer
The purpose of this study is to create a new blood test for patients with blood cancer. We want to see if this new blood test can help predict which patients will benefit from a type of immunotherapy called CAR T-cell therapy. We are looking for volunteers with blood cancer that are eligible to receive CAR T-cell therapy. The study team will provide more information.
Study Topics
Cancer Cancer: Blood Cancer: Leukemia Cancer: Lymphoma Cancer: Myeloma
Helping Myeloma Patients Stay Healthy After CAR-T Therapy
The purpose of this study is to learn more about a medicine called iberdomide. We want to see if it is safe to take after a certain cancer treatment called CAR-T. Researchers want to know if this medicine can help keep multiple myeloma from coming back. They also want to see if this new treatment works better than just watching the cancer without giving more medicine.
Study Topics
Using Ide-Cel to Treat Multiple Myeloma
The purpose of this research is to see if idecabtagene vicleucel (ide-cel) is safe and useful to treat participants with multiple myeloma.
Study Topics
Testing New Treatments for Multiple Myeloma
The purpose of this study is to test a new mix of drugs for people with a type of blood cancer called multiple myeloma. We want to see if adding a new drug, belantamab mafodotin, to the usual treatment of carfilzomib, lenalidomide, and dexamethasone works better. This study will help doctors find out if this new mix helps patients live longer and feel better.
Study Topics
Testing the Drugs Inavolisib and Phesgo for Advanced Breast Cancer Treatment
This study aims to learn about a new drug combination for breast cancer that has spread. We want to compare the side effects of the drugs inavolisib and Phesgo with a placebo and Phesgo. Volunteers must have HER2-positive PICK3CA-mutated breast cancer, study team will provide more details.
Study Topics
Treating Vulvar Dysplasia with a New Surgical Treatment
This study is being done to see if a surgical treatment, Frozen-Section Directed Excision, is better at treating vulvar dysplasia than the usual treatment.
Study Topics
Studying the Drug JNJ 88549968 for Patients with Myeloproliferative Neoplasms
Myeloproliferative neoplasms are blood cancers caused by changes in bone marrow cells. This study aims to learn more about the drug JNJ-88549968 to treat these cancers. We want to find a safe dose and see how long it stays in the body and how the body reacts to it.
Study Topics
Studying the Drug JNJ-90014496 for Patients with B Cell Non-Hodgkin Lymphoma
This study aims to learn more about the drug JNJ-90014496. We want to see if this drug is safe and helpful for treating patients with B cell Non-Hodgkin Lymphoma that has come back or hasn't responded to treatment.
Study Topics