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Treating Relapsing Multiple Sclerosis with BIIB091
The purpose of this study is to find out how well a new drug called BIIB091 works for treating relapsing multiple sclerosis. We also want to find out how well the body can handle taking the study drug.
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Finding Therapies that Improve Survival for Patients with Glioblastomas
The purpose of this research is to test multiple study treatments for glioblastoma. We want to find out if any of these study treatments can improve how long patients live.
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Learning More About the NeuroBlate System to Treat Cancer that Has Spread to the Brain
The purpose of this study is to better understand how well the NeuroBlate System works for treating brain metastases. The system will be used along with laser interstitial thermal therapy (LITT). The NeuroBlate System uses laser light energy to heat and destroy the tumor. The LITT procedure includes a biopsy of brain tissue. The procedures are considered to be minimally invasive.
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High Blood Pressure in Children and Teenagers
The purpose of this study is to understand what causes high blood pressure in young people. We also want to learn more about how high blood pressure can cause damage to the heart and kidneys.
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Healthy Volunteers Heart Health Children, Infants, Teen Health
Comparing Stereotactic Radiosurgery to Whole Brain Radiotherapy
The purpose of this study is to find out if stereotactic radiosurgery can reduce your symptoms and lower the chance of the cancer growing or getting worse. Stereotactic radiosurgery is commonly used to treat brain tumors. It is a one or two-day outpatient procedure. A high dose of radiation is delivered to small spots in the brain not including the normal brain. We want to find out if this approach is better or worse than the usual approach for cancer that has spread to the brain.
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Treating Recurrent Grade IV Glioma with NEO100
The purpose of this study is to find out how well the study drug, NEO100, works for treating glioblastoma that has returned after treatment.
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Can Immunotherapy Help Non-Small Cell Lung Cancer Patients Improve Physical Function
The purpose of this study is to see if treatment with immunotherapy can help lung cancer patients who get tired easily and struggle with some daily tasks.
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Is it More Helpful to Give Children with Germ Cell Tumors Chemotherapy on a Faster Schedule
A germ cell tumor is a type of cancer found in the ovaries for females or the testes for males. This tumor may also be found in the pelvis along the tailbone, chest, abdomen, and other structures of the body. Chemotherapy is the medicine used to fight cancer. We want to find out if giving children with germ cell tumors chemotherapy on a faster schedule is effective.
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A study on the Effectiveness of Four Drugs (Vismodegib, GSK2256098, capivasertib, abemaciclib) Against Meningioma Tumors
The purpose of this study is to see if tumor genetic testing would be helpful when selecting a treatment for meningioma. The usual treatment for meningioma is the same for all patients and not based on tumor genetic testing. This study will look at the tissue of your tumor to see what types of mutations it has across different types of genes. Study treatment will be based on the type of altered genes in your tumor.
Study Topics
Combination Chemotherapy for Newly Diagnosed and Relapsed Wilms Tumor
The purpose of this study is to find out if we can improve treatment for those with Wilms tumors. We will be testing three different combinations of radiation and chemotherapy. The combination you receive will depend on your type of Wilms tumor.
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Cancer Cancer: Kidney, Liver, Pancreas Children, Infants, Teen Health
How the Brain Processes Information
The purpose of this study is to look at how the human brain processes information. We want to know how the human brain responds to different stimuli, how those stimuli make you feel, and how your feelings guide your decisions.
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Study Identifying Genetic Markers of Ovarian Cancer
The purpose of this study is to learn more about biological markers found in tissue, blood, and fluids. These markers may be able to tell us how severe a cancer can be and how well a cancer is responding to treatment.
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I-SPY 2 TRIAL: Study of New Drugs to Treat Breast Cancer Before Surgery
The purpose of this study is to learn more about giving the best treatment at the right time. Treatment on this study will be given before surgery. This allows us to better understand how different people's breast cancers respond to commonly used chemotherapy with or without new drugs.
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A Study of the Drug Fluticasone Propionate and Albuterol Sulfate to Treat Asthma
The purpose of this study is to learn more about the study drug Fluticasone Propionate and Albuterol Sulfate. We want to see how well the study drug works for treating symptoms of asthma and preventing severe asthma attacks.
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Learning More About Treating Gastric, Gastroesophageal Junction and Pancreatic Tumors with ASP2138
The purpose of this study is to find out how well the study drug, ASP2138, works for treating gastric, gastroesophageal junction or pancreatic tumors. We also want to learn more about the side effects that may be caused by the study drug.
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Cancer Cancer: Kidney, Liver, Pancreas Cancer: Stomach and Intestines
Studying CereGate Therapy in Patients Diagnosed with Parkinson's Disease
The purpose of this study is to learn more about a new therapy called CereGate. We want to see if this type of therapy can reduce freezing movements in patients with Parkinson's Disease.
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How the Brain Makes Decisions in Patients with Parkinson's Disease
The purpose of this study is to look at how the brain responds to information when it comes to decision making.
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Study to Better Understand Drug Induced Liver Injury
The purpose of this study is to try to understand why some people have liver injury after taking certain drugs or supplements. This is not a treatment study.
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Testing the Use of Chemo Before and After Pancreatic Cancer Surgery
We would like to find out if chemo before and after pancreatic cancer surgery will help keep the cancer away.
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Treating Recurrent Urethral Stricture with Tissue Engineered Urethral Construct
The purpose of this study is to understand the experiences of people with a special type of inherited kidney disease. Taking part in this research will involve one 60-minute interview.
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