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Study of Inherited Kidney Disease
The purpose of this study is to understand the experiences of people with a special type of inherited kidney disease. Taking part in this research will involve one 60-minute interview.
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Treating Recurrent Urethral Stricture with Tissue Engineered Urethral Construct
The urethra is a thin tube-like structure that allows urine to leave your bladder. Urethral stricture is a narrowing of the urethra that affects the flow of urine out of your bladder. The purpose of this study is to find out if an engineered urethra made from your own cells can be surgically implanted safely. We also want to find out if the implanted urethra helps improve urinating. The new urethral segment will be created using cells from your bladder, which are the same cells that make up your urethra.
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Studying Ways to Improve Physical Activity in Young Adult Cancer Survivors
The purpose of this study to test four different ways to improve physical activity in young adult cancer survivors. We want to learn more about each approach and see which one will work best.
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Learning More About the Study Drug GP-2250 for Treating Advanced Pancreatic Adenocarcinoma
The purpose of this study is to find out how the study drug GP-2250 may affect advanced pancreatic cancer. The study drug will be given along with the usual treatment Gemcitabine. We want to see if this combination works better than the usual approach. We also want to learn more about possible side effects.
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Internet-Based Program to Help Cancer Survivors Manage Pain
The purpose of this study is to learn more about an internet-based pain program combined with pain education. We want to see if the pain program and education can help reduce pain and improve impact on daily activities. We also want to see if this approach is better or worse than the usual approach.
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Study to Find Out How Well Inebilizumab Works for Treating Brain Inflammation
The purpose of this study is to find out how well the study drug, Inebilizumab, works for people newly diagnosed with anti-NMDAR encephalitis. Anti-NMDAR is brain inflammation caused by antibodies.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults
This purpose of this study is to find out if a drug called atorvastatin can help older adults live well for longer by preventing dementia, disability or heart disease.
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Study of Decreasing Drinking in Heavy Alcohol Users
The purpose of this study is to see how a tool called transcranial magnetic stimulation (TMS) may change the brain's response to alcohol related pictures. TMS is a technique that does not require surgery or anesthesia. The treatment may help reduce alcohol cravings in people with alcohol use disorder.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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IGROOVE: A Dance and Music Study for Older Adults with Memory Concerns
The purpose of the study is to see how music and dance may affect fitness and brain health. The study will include people who are concerned about their memory but have not been diagnosed with memory loss.
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The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Looking at the Connection Between Endometriosis and Pregnancy Loss
The purpose of this study is to understand why some women repeatedly lose pregnancies. This study will look at tissue and blood samples from women with unexplained recurrent pregnancy loss.
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Concussion Symptoms in Young People Ages 11-17
The purpose of this study is to learn more about concussion symptoms in young people ages 11 to 17. This may help us develop future treatments.
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Studying the Drug Metformin for Older Patients with Heart Failure
This study wants to see if the medicine Metformin XR can help older people with this heart problem. We also want to learn about the side effects and see if it can make their health better.
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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV), diabetes, COPD and other chronic health conditions. We want to learn more about their experience with medication regimens.
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Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
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