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A Study of the Drug Valacyclovir for Babies at Risk of Herpes
The purpose of this study is to learn more about the study drug Valacyclovir. We want to figure out the best amount of the study drug that is needed for babies who may have been exposed to herpes when they were born.
Study Topics
Testing the Combination of Abemaciclib and Olaparib for Treatment of Ovarian Cancer
The purpose of this study is to learn more about using abemaciclib and olaparib to treat ovarian cancer that has returned. This study tests different doses of the drugs to find the highest dose that is safe and well tolerated. We also want to see what side effects may occur.
Study Topics
Study of the Effectiveness of the Drug Mosunetuzumab with Lenalidomide, Compared to the Drug Rituximab with Lenalidomide in Patients with Follicular Lymphoma
The purpose of this study is to compare the effects, good or bad, of mosunetuzumab administered in combination with lenalidomide versus rituximab administered in combination with lenalidomide in patients with follicular lymphoma (FL). FL is a type of cancer that affects white blood cells, which are part of the body's immune system.
Study Topics
Studying the Drug Metformin for Older Patients with Heart Failure
This study wants to see if the medicine Metformin XR can help older people with this heart problem. We also want to learn about the side effects and see if it can make their health better.
Study Topics
Testing the Addition of a Third Medication to the Usual Treatment for Gastroesophageal Adenocarcinoma
The purpose of this study is to find out if the drug irinotecan can extend life after the diagnosis of cancer in the stomach, esophagus, or gastroesophageal junction. Irinotecan will be added to the usual treatment. We want to find out if this approach is better or worse than the usual treatment.
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Concussion Symptoms in Young People Ages 11-17
The purpose of this study is to learn more about concussion symptoms in young people ages 11 to 17. This may help us develop future treatments.
Study Topics
Learning More About How Cells Age in Your Muscle
The purpose of this research is to understand how the cells in your muscle age over time.
Study Topics
Testing Different Courses of Hormone Therapy Depending on the Type of Prostate Cancer
The purpose of this study is to test different courses of hormone therapy depending on the type of prostate cancer. We are doing this study to find out if these approaches are better, similar, or worse than the usual approach for your type of prostate cancer.
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Testing How Oxytocin Effects Response to Heat
Oxytocin is a hormone made in the brain that transmits messages. The purpose of this study is to test the effects oxytocin may have on thermal testing.
Study Topics
Treating Early Alzheimer's Disease with the Study Drug CT1812
The purpose of this study is to find out if the study drug, CT1812, can slow memory decline. We want to see how well it works for people with mild memory decline due to Alzheimer's disease and dementia.
Study Topics
Comparing Single Dose to Multiple Doses of Radiation for Patients with Cancer that Has Spread to the Brain
The purpose of this study is to find out if there are less side effects when radiation therapy is given to small areas of brain cancer over several days compared to one day. We want to find out if this approach is better or worse than the usual approach.
Study Topics