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Study of Quick Start Durvalumab for Treating Stage III Non-Small Cell Lung Cancer
Durvalumab is usually started 30 days or more after radiation treatment. The purpose of this study is to find out if it is possible to start Durvalumab within 14 days after radiation treatment. We want to see how the quick start affects you and your cancer.
Study Topics
Testing RINVOQ for the Treatment of Adults with Lupus
The purpose of this study is to find out how well the study drug RINVOQ works for treating adults with systemic lupus erythematosus. We also want to find out how safe the study drug is for patients. RINVOQ is an FDA approved medication for other conditions.
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Testing the Combination of Abemaciclib and Olaparib for Treatment of Ovarian Cancer
The purpose of this study is to learn more about using abemaciclib and olaparib to treat ovarian cancer that has returned. This study tests different doses of the drugs to find the highest dose that is safe and well tolerated. We also want to see what side effects may occur.
Study Topics
Testing Different Courses of Hormone Therapy Depending on the Type of Prostate Cancer
The purpose of this study is to test different courses of hormone therapy depending on the type of prostate cancer. We are doing this study to find out if these approaches are better, similar, or worse than the usual approach for your type of prostate cancer.
Study Topics
Comparing Single Dose to Multiple Doses of Radiation for Patients with Cancer that Has Spread to the Brain
The purpose of this study is to find out if there are less side effects when radiation therapy is given to small areas of brain cancer over several days compared to one day. We want to find out if this approach is better or worse than the usual approach.
Study Topics
Treating Early Alzheimer's Disease with the Study Drug CT1812
The purpose of this study is to find out if the study drug, CT1812, can slow memory decline. We want to see how well it works for people with mild memory decline due to Alzheimer's disease and dementia.
Study Topics
Comparing Two Surgical Procedures to Reduce the Risk of Ovarian Cancer
The purpose of this study is to compare two different surgeries to reduce the risk of ovarian cancer. The study will look at the process used to decide which surgery is best for the patient. It will also look at symptoms that occur after removal of the ovaries.
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A Registry for People taking Humira for Ulcerative Colitis
The purpose of this study is to collect long-term data on people taking Humira for ulcerative colitis. This registry only involves the collection and storage of data. There are no procedures or treatments required. There are no additional risks associated with this collection of data.
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Study of Memory Loss in the African-American Population
The purpose of this study is to better understand what causes memory loss in African Americans. We hope this type of research will result in improved diagnosis, better treatment and possibly prevention.
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Using Camizestrant for Hormone Therapy to Treat ER+/HER2- Breast Cancer
The purpose of this study is to learn more about the study drug camizestrant. We want to see how well the study drug works at stopping the cancer from coming back compared to the usual treatment.
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Collecting Data from Study Volunteers with Pulmonary Fibrosis and Fibrosing Interstitial Lung Disease
The purpose of this registry is to collect data to be used for future research on pulmonary fibrosis and other conditions that cause scarring in the lungs. This is not a treatment study. We will collect information from you through interviews, questionnaires, and medical records. Blood draw will be required around every six months. Your information will be collected for at least 3 years.
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Learning More About the Study Drug, XEN1101, for Treating Focal Onset Seizures
The purpose of this study is to find out if the study drug, XEN1101, can reduce seizure frequency. We also want to see if it is safe to use.
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Causes of Obesity and Weight Loss
The purpose of this study is to gather data to help learn more about the causes of obesity. We also want to learn more about the things that can affect weight loss.
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Using Muscadine Grape Extract to Help with Fatigue Caused by Prostate Cancer Treatment
Men being treated for prostate cancer can experience fatigue. The purpose of this study is to find out if muscadine grape extract can help improve that fatigue.
Study Topics
Learning More About the Study Drug, XEN1101, for Treating Primary Generalized Tonic-Clonic Seizures
The purpose of this study is to find out if the study drug, XEN1101, can reduce seizures. We also want to see if it is safe to use.
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How Brain Activity Relates to Your Ability to Shift Attention in Response to Images
The purpose of this study is to look at how brain activity is related to your ability to shift attention when visual cues change. You will be asked to view specified images while receiving an MRI scan.
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Using Ultrasound to Detect Neuropathy Caused by Chemotherapy with Oxaliplatin
The purpose of this study is to find out if ultrasound can be used to diagnose damage to nerves caused by the drug Oxaliplatin. Taking part in this study requires one visit. The visit will include ultrasound of the nerve, nerve conduction test, skin biopsy, and examination of your nerves.
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Study of a Web-based Tool to Diagnose Parkinson's Disease
The purpose of this study is to see how well a web-based software tool called Automated Imaging Differentiation of Parkinsonism works. The software will provide accurate diagnosis between Parkinson's disease, multiple system atrophy parkinsonian, and progressive supranuclear palsy.
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Comparing the Drugs Aspirin and Apixaban to See How Well They Work at Preventing Stroke or Death
The purpose of this study is to look at the how the drugs apixaban and aspirin effect patients with irregular heartbeat and recent brain bleeding. We also want to find out which is better at preventing future strokes and death.
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Can You Help the Tooth Fairy?
The purpose of this study is to learn more about how early life exposures can affect a child's or young adult's health. These exposures can include different things such as medications and foods. This study will be done completely online. The required baby tooth and saliva samples will be sent in using prepaid envelopes.
Study Topics
Healthy Volunteers Allergies and Immunity Stomach and Intestines Children, Infants, Teen Health