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A Study of the Drug ABBV-383 for Patients with Multiple Myeloma
The purpose of this study is to learn more about the study drug ABBV-383 for patients with multiple myeloma that has returned or has not responded to treatment. We want to find the best dose and learn about the safety and effects of the study drug.
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Treating Recurrent Urethral Stricture with Tissue Engineered Urethral Construct
The urethra is a thin tube-like structure that allows urine to leave your bladder. Urethral stricture is a narrowing of the urethra that affects the flow of urine out of your bladder. The purpose of this study is to find out if an engineered urethra made from your own cells can be surgically implanted safely. We also want to find out if the implanted urethra helps improve urinating. The new urethral segment will be created using cells from your bladder, which are the same cells that make up your urethra.
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Studying Ways to Improve Physical Activity in Young Adult Cancer Survivors
The purpose of this study to test four different ways to improve physical activity in young adult cancer survivors. We want to learn more about each approach and see which one will work best.
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Head Trauma Among Student Athletes
We want to learn about how head movement during a contact sport-related hit to the head affects the brain. Contact sports include those which may involve contact to the head during play such as football and soccer.
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Healthy Volunteers Brain and Memory Children, Infants, Teen Health
Learning More About the Study Drug GP-2250 for Treating Advanced Pancreatic Adenocarcinoma
The purpose of this study is to find out how the study drug GP-2250 may affect advanced pancreatic cancer. The study drug will be given along with the usual treatment Gemcitabine. We want to see if this combination works better than the usual approach. We also want to learn more about possible side effects.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults
This purpose of this study is to find out if a drug called atorvastatin can help older adults live well for longer by preventing dementia, disability or heart disease.
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Internet-Based Program to Help Cancer Survivors Manage Pain
This purpose of this study is to find out if a drug called atorvastatin can help older adults live well for longer by preventing dementia, disability or heart disease.
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Study to Find Out How Well Inebilizumab Works for Treating Brain Inflammation
The purpose of this study is to find out how well the study drug, Inebilizumab, works for people newly diagnosed with anti-NMDAR encephalitis. Anti-NMDAR is brain inflammation caused by antibodies.
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Using the Study Drugs M1774 and Avelumab to Treat Merkel Cell Skin Cancer
The purpose of this study is to learn more about the study drug M1774. We want to see how well the study drug treats Merkel cell cancer when used alone and when combined with Avelumab. We want to find out if either approach is better or worse than the usual treatment.
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Study of Decreasing Drinking in Heavy Alcohol Users
The purpose of this study is to see how a tool called transcranial magnetic stimulation (TMS) may change the brain's response to alcohol related pictures. TMS is a technique that does not require surgery or anesthesia. The treatment may help reduce alcohol cravings in people with alcohol use disorder.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Learning More About a New Treatment for Diabetic Macular Edema
Diabetic macular edema (DME) is the gathering of fluid in the retina area of the eye. The purpose of this study is to see how well the study drug, RO7200220, works for treating DME.
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IGROOVE: A Dance and Music Study for Older Adults with Memory Concerns
The purpose of the study is to see how music and dance may affect fitness and brain health. The study will include people who are concerned about their memory but have not been diagnosed with memory loss.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Looking at the Connection Between Endometriosis and Pregnancy Loss
The purpose of this study is to understand why some women repeatedly lose pregnancies. This study will look at tissue and blood samples from women with unexplained recurrent pregnancy loss.
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Concussion Symptoms in Young People Ages 11-17
The purpose of this study is to learn more about concussion symptoms in young people ages 11 to 17. This may help us develop future treatments.
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