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Collecting Data on Patients with Cystic Fibrosis
Study Topics
Genetic Disorders Lung Health Children, Infants, Teen Health
Improving COPD Care for Cancer Patients
Chronic obstructive pulmonary disease (COPD) is a lung disease that makes it hard to breathe because the airways are swollen and narrow. The purpose of this study is to create a new way to help cancer patients who also have COPD. We want to make their treatment easier and improve their care. Our study will look at how well this new care plan works.
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Studying Hair Loss in Women of African Descent during Chemotherapy
The purpose of this study is to understand hair loss in African American women who are getting chemotherapy for breast cancer. We want to find out how common different types of hair loss are with chemotherapy. We also want to learn about the participants' health history, medical information, and hair styling habits.
Study Topics
Minority Health Skin, Hair, Nails Women's Health Cancer Cancer: Breast
Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
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Learning More About Treating Myelofibrosis and Anemia with the Study Drug DISC-0974
Myelofibrosis is a rare blood disorder that can cause scar tissue to build up in the bone marrow. This can lead to anemia. Anemia can result in tiredness and general discomfort. The purpose of this study is to see who well the study drug DISC-0974 works for the treating myelofibrosis and anemia. We also want to learn more about the side effects the study drug may cause.
Study Topics
Comparing Different Medication Combinations for Brain Artery Narrowing
The purpose of this study is to see how well the combination of study drugs, ticagrelor and aspirin or rivaroxaban and aspirin, help people who have had a stroke from narrowed brain artery. We want to see if the study drugs are better than the usual treatment in preventing another stroke or death.
Study Topics
Studying the Long-Term Usefulness of a Parkinson's Disease Treatment
The purpose of this study is to see how well the drug ABBV-951 works for people with advanced Parkinson's Disease over a long time. We will look at how the drug affects movement, daily activities, and changes in the disease over three years. We need volunteers who have never taken the drug before or who have used it before. The study team will give more details.
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Studying Two Treatments for Early Stage Breast Cancer
The purpose of this study is to learn more about adding chemotherapy to hormone treatment for breast cancer. We will compare two common treatments to see which works better. The goal is to find out if adding chemotherapy can prevent the cancer from returning and learn more about the possible side effects. We are looking for volunteers who have early-stage breast cancer, are HER2-negative, and have not gone through menopause yet.
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Comparing Treatments in Children Newly Diagnosed with Crohn's Disease
The purpose of this study is to learn more about why some children with Crohn's disease heal their bowel inflammation after one type of treatment and why others do not. Volunteers must have suspected Crohn's disease.
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Studying a New Vaccine for Brain Cancer
The purpose of this study is to learn more about a new vaccine created from tumor tissue. We want to see if it can help treat patients with brain cancer after surgery, chemotherapy, and radiation. The vaccine may help your body fight cancer better. The study will also help doctors learn how to improve treatment for future patients.
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Studying a Treatment for Patients with Severe Sjögren's Disease
Sjögren's disease is an autoimmune disorder that causes dry eyes and mouth. The purpose of this study is to learn about a new treatment for patients with this disease. We want to find out if the treatment, called nipocalimab, is safe and useful. To do this, we will compare the effects of nipocalimab to a placebo to see if it works.
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Testing a New App for Radiation Skin Rash in Head and Neck Cancer Patients
We want to learn about a new mobile app called MyCap for people with head and neck cancer who are getting radiation therapy. The study will check if the app can collect information about skin rashes caused by radiation. Volunteers will need to use their own mobile device to access the app. You are invited to join this study because you have head and neck cancer and will get radiation therapy.
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Studying a New Medicine for Lennox-Gastaut Syndrome
Lennox-Gastaut Syndrome is a rare and serious kind of epilepsy that causes many types of seizures. The purpose of this study is to learn more about a medicine called EPX-100 to see if it helps people with this epilepsy. Our researchers want to find out how well the medicine works, what side effects it might have, and how it could help people in the future.
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Comparing Metformin and Insulin for Gestational Diabetes
The purpose of this study is to see if the medicine Metformin works as well and is as safe as insulin for treating diabetes during pregnancy. We also want to know which treatment pregnant people with diabetes like better and how it affects their pregnancy.
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Testing a Device to Prevent Stroke in Patients with Patent Foramen Ovale
The purpose of this study is to test a new study device called the GORE CARDIOFORM Septal Occluder. We want to see if this device can help patients with this heart condition by closing the hole in the heart and preventing another stroke.
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Studying a New Bladder Pain Treatment
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a condition that causes pain in the bladder and makes you feel like you need to pee often, even if your bladder is not full. The purpose of this study is to learn more about a new medicine called VNX001 for this condition. Our researchers want to learn if it is safe and works well for patients.
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Studying a New Treatment Plan for Patients with Large B-cell Lymphoma or Grade IIIB Follicular Lymphoma
We are looking for volunteers with Grade IIIB Follicular or Relapsed/Refractory Diffuse Large B-cell Lymphoma. The purpose of this study is to see if we can reduce the chance of your cancer growing or spreading by adding more treatment to the usual therapy. We are doing this study to see if this new approach is better or worse than the usual approach for patients who are getting CAR T-cell therapy.
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A Study of the Drug Seladelpar for Liver Disease and Scarring of the Liver
The purpose of this study is to learn more about the study drug Seladelpar. We want to see if the study drug can help treat patients with chronic liver disease and scarring of the liver. We will look at changes in overall health, severity of symptoms, and progression of disease.
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Studying Money Stress Among Patients with Leukemia
The purpose of this study is to see if helping people with money problems during cancer treatment can make them feel better and stay healthier. People in the study will answer questions about their health, feelings, and money. The goal is to find out if special help with money makes a difference.
Study Topics