Search Studies
Study of DSP-5336 for Treatment of Leukemia
Acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and acute leukemia are types of cancer of the blood and bone marrow. This study will help us learn more about a new drug, DSP-5336, that is being tested for treatment of AML, ALL and acute leukemia. The purpose of this study is to find out how safe DSP-5336 is at different doses.
Study Topics
A Study of the Drug Upadacitinib for Children with Ulcerative Colitis
The purpose of this study is to learn more about the study drug upadacitinib for treating ulcerative colitis, a type of bowel disease. We want to find out if the study drug is safe and works well for children with ulcerative colitis who have not had a response to other types of treatment.
Study Topics
How Myotonic Dystrophy Type 2 Affects the Brain
Myotonic dystrophy affects the muscles and other body systems. The purpose of this study is to look at the impact myotonic dystrophy type 2 has on the brain. We also want to look at brain-based symptoms like problems with thinking, memory or motivation.
Study Topics
Study of Canakinumab for Treating Myelofibrosis
The purpose of this study is to find out how well Canakinumab works for treating myelofibrosis.
Study Topics
Learning More About Asthma and Coach McLungs, an Asthma Intervention
The purpose of this study is to learn more about asthma and to explore a new way to treat it with Coach McLungs. Coach McLungs is an asthma health communication model that allows patients and healthcare providers to work together to make health care related decisions. Your participation in this research will involve one interview.
Study Topics
The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
Study Topics
Learning More About a New Study Drug for Treating Uveitic Macular Edema
The layer at the back of the eye is called the retina. Build?up of fluid in the retina is called uveitic macular edema. The purpose of this study is to find out if the study drug RO7200220 can help control inflammation and remove the fluid build-up in the retina to help your vision.
Study Topics
Study on Statin Use in Older Adults
Statins are medicines that lower bad cholesterol in the body. They help prevent heart attacks and strokes. This study wants to find out if taking statins can help older adults live longer and healthier by preventing dementia, disability, or heart disease.
Study Topics
Aging Healthy Volunteers Heart Health Screening and Prevention
Study of Second Look Laparoscopy with Hyperthermic intraperitoneal chemotherapy (HIPEC) in Patients with Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
After their first surgery, patients often have a procedure called second look reassessment surgery. This surgery allows doctors to look inside your body and check for signs of cancer. The purpose of this study is to see how well it works to give HIPEC during the second look surgery. HIPEC is a type of chemotherapy inserted directly into your abdomen at the time of surgery. We want to monitor any effects that this has on your health.
Study Topics
Women's Health Cancer Cancer: Rare Cancers Cancer: Women's Cancer
Finding Out How Well Selinexor Works for Treating Brain Cancer
The purpose of this study is to find the safest dose of the study drug, Selinexor. We also want to find out if adding the study drug is better than the usual treatment for brain cancer.
Study Topics
Learning More About Saliva and Dry Mouth
The purpose of this study is to find out what parts of saliva might cause people to feel like they have a dry mouth. By figuring this out, we can understand dry mouth better and treat it more effectively.
Study Topics
Healthy Volunteers Needed to Help Learn More About How Oxytocin May Affect the Way People Sense Heat and Vibration
The purpose of this study is to learn more about the effects oxytocin. Oxytocin is a naturally occurring hormone made in the brain that transmits messages. We want to learn more about how oxytocin may affect the way a person feels heat and vibration. For this study Oxytocin will be given through an IV.
Study Topics
Study of Selinexor for Treating High-Grade Glioma in Pediatric Patients
A glioma is a type of cancer that occurs in the brain or spine. Diffuse intrinsic pontine glioma is a type of high-grade glioma. The purpose of this study is to look at how well selinexor works when given to children and young adults with high-grade glioma or diffuse intrinsic pontine glioma. We also want to find the highest dose of selinexor that we can give safely along with radiation therapy.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Children, Infants, Teen Health
Improving the Care and Health of Children, Adolescents, and Young Adults with Inflammatory Bowel Disease
The purpose of this study is to improve the care and health for children, teens, and young adults with IBD (Inflammatory Bowel Disease). We want to gather information from your regular care visits to help improve the care for patients with inflammatory bowel disease. For example, we could learn which type of medication works best for treating this disease.
Study Topics
Finding Therapies that Improve Survival for Patients with Glioblastomas
The purpose of this research is to test multiple study treatments for glioblastoma. We want to find out if any of these study treatments can improve how long patients live.
Study Topics
Learning More About Speech Profiles after a Stroke
The purpose of this study is to learn more about speech profiles among stroke survivors and healthy volunteers. Understanding more about speech profiles can help customize treatment.
Study Topics
Using Cancer Cells in the Blood to Determine the Type of Chemotherapy that Will Benefit Colon Cancer Patients After Surgery
The purpose of this study is to help us learn more about using circulating tumor DNA (ctDNA) results to decide what chemo to offer patients after colon cancer surgery. ctDNA is DNA that has been released from tumor cells into your blood. Finding ctDNA in your blood means that there are likely small amounts of cancer after surgery. This study will help us find out if using ctDNA results to decide on treatment is better than the usual approach.
Study Topics
Study to Learn More About Severe Asthma
The purpose of this study is to learn more about severe asthma. We will compare people with severe asthma to those with milder forms of asthma.
Study Topics
Collecting Data for Parkinson's Disease Research
The purpose of this study is to gather information on people with Parkinson's disease through a patient registry. The registry will collect genetic information from people with Parkinson's, those at risk, and others without the disease. The registry will help improve understanding and care for Parkinson's disease.
Study Topics
Adding Radiation Therapy to the Usual Treatment for Small Cell Lung Cancer
This study is being done to find out if we can slow lung cancer from growing or spreading. We will try to do this by adding radiation therapy to the usual treatment.
Study Topics