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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV), diabetes, COPD and other chronic health conditions. We want to learn more about their experience with medication regimens.
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Studying the Drug Metformin for Older Patients with Heart Failure
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV), diabetes, COPD and other chronic health conditions. We want to learn more about their experience with medication regimens.
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Understanding Headaches Related to Having Large Breasts
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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Finding Out How Well Adding a Third Medication to Treatment Works for Treating Advanced Rectal Cancer
The purpose of this study is to find out if we can increase the likelihood of your tumor disappearing by adding a third drug to the usual treatment. We want to find out if this approach is better or worse than the usual approach.
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Using Special Eyeglasses to Detect Absence Seizures in Children
The purpose of this study is to learn more about a new type of eyeglasses. We want to find out if eyeglasses can tell if a child is having absence seizures or having attentional difficulties.
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Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
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Adding Tazemetostat to the Usual Treatment for Melanoma
The purpose of this study is to find out if the study drug, tazemetostat, can keep your melanoma from getting worse. We also want to see if the study drug alone is better or worse than adding the study drug to the usual treatment.
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Learning More About Treating Glioma with the Study Drug OKN-007
The purpose of this study is to find out how well the study drug, OKN-007, works for treating glioma. We also want to determine what dose is safe and well tolerated.
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Early Chronic Obstructive Pulmonary Disease (COPD) in Younger Patients
Chronic obstructive pulmonary disease (COPD) is a lung disease that causes blocked airflow from the lungs. The purpose of this study is to learn more about COPD in younger people that are at risk.
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Adding the Study Drug Apalutamide to the Usual Treatment for Prostate Cancer After Surgery
The purpose of this study is to find out if we can extend the time without your prostate cancer spreading by adding the study drug to the usual treatment. We want to find out if this approach is better or worse than the usual approach for your prostate cancer.
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Testing the Study Drug STP0404 for Treatment of HIV-1
The purpose of this study is to find out if the study drug, STP0404, decreases the amount of HIV virus in your body. We also want to learn more about the possible side effects of the study drug.
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Study of Non-Invasive Therapy for Female Patients with Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to see how well a non-invasive therapy works to treat interstitial cystitis/bladder pain syndrome. The therapy uses a device that sends magnetic waves into the body which may help the body better heal itself. We want to find out if the study therapy can reduce pelvic pain and urinary symptoms.
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Learning More about COVID-19 Testing and Pandemic Response among Black and African American Communities
The purpose of this study is to learn more about what makes it easier or harder for African Americans to engage in COVID-19 testing and pandemic response. We want to gather information that will lead to better health for everyone.
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New Test to Diagnosis Mycosis Fungoides
Mycosis Fungoides (MF) is a disease that affects the skin. The purpose of this study is to develop a new test to help diagnose MF.
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Learning More About Adding TRC102 to the Usual Non-Small Cell Lung Cancer Treatment
The purpose of this study is to learn more about the study drug, TRC102. We want to see how it can affect Stage III lung cancer. TRC102 will be added to the usual treatment. The addition of TRC102 to the usual treatment could stabilize your cancer and lengthen the time you can live. This study will help the us find out if this approach is better than the usual approach.
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Study of Bempedoic Acid for Treating High Cholesterol in Children
Heterozygous familial hypercholesterolemia (HeFH) is an inherited genetic disorder. It causes dangerously high cholesterol levels. This study will see if bempedoic acid works at lowering cholesterol in kids with HeFH. Bempedoic has been tested in adults, but it has not been tested in children or young adults yet.
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Finding Out How Well Selinexor Works for Treating Brain Cancer
The purpose of this study is to find the safest dose of the study drug, Selinexor. We also want to find out if adding the study drug is better than the usual treatment for brain cancer.
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Learning More About a New Study Drug for Treating Uveitic Macular Edema
The layer at the back of the eye is called the retina. Build?up of fluid in the retina is called uveitic macular edema. The purpose of this study is to find out if the study drug RO7200220 can help control inflammation and remove the fluid build-up in the retina to help your vision.
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Treating Multiple Myeloma with Study Drug ABBV-383
The purpose of this study is to see how the study drug, ABBV-383, affects patients with multiple myeloma that has returned or been difficult to treat. Some volunteers will get increasing doses of the study drug. We want to see if the increasing doses can reduce a side effect known as cytokine release syndrome.
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