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A Study of the Drug ABBV-383 for Patients with AL Amyloidosis
The purpose of this study is to learn more about the study drug ABBV-383 in patients with amyloidosis. We want to find the best dose and learn about the safety and effects of the study drug.
Study Topics
Study of the Drug AMG 355 in Patients with Advanced Solid Tumors
The purpose of this study is to learn more about the study drug AMG 355. We want to see how well the study drug works for treating advanced solid tumors. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Cancer Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Skin Cancer: Stomach and Intestines
Testing a New Treatment for Myeloproliferative Disorders
The purpose of this study is to see how well the study drug, INCA033989, works for treating myeloproliferative disorders. We want to find what effects, if any, this therapy may have on people. We also want to find out what is the highest dose that can be given without causing severe side effects.
Study Topics
Learning More About Intestinal Health in Infants and Children with a New Imaging Device
The purpose of this study is to learn more about a new type of imaging device called the iThera MSOT Acuity. We want to find out how well the device works for measuring intestinal health.
Study Topics
Learning More About Treating Plaque Psoriasis with Deucravacitinib
The purpose of this study is to find out how well the study drug, deucravacitinib, works for treating psoriasis on the palms, soles, and genital area. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
A study of the Drug Budesonide, Glycopyrronium, and Formoterol Fumarate to Treat Chronic Obstructive Pulmonary Disease
The purpose if this study is to learn more about the study drugs Budesonide, Glycopyrronium, and Formoterol Fumarate. We want to see how well the study drugs work for preventing chronic obstructive pulmonary disease flare-ups.
Study Topics
Testing a Radiation-Based Treatment for Prostate Cancer that has Spread
The purpose of this study is to find out if radiation treatment with Lutetium Lu 177 Dotatate can shrink or slow the growth of prostate cancer. We want to find out if this approach is better or worse than the usual approach.
Study Topics
Learning More About Treating Nonrelapsing Secondary Progressive Multiple Sclerosis with Frexalimab
The purpose of this study is to see if the study drug, Frexalimab, can keep multiple sclerosis from getting worse. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Treating Uncontrolled Seizures with the Study Drug NRTX-1001
The purpose of this study is to learn more about treating uncontrolled seizures with the study drug NRTX-1001. We want to see how the study drug works and find out what side effects may be caused.
Study Topics
Study of COVID19 Infections Using At-Home Rapid Diagnostic Test Kits and Online Data Gathering
The purpose of this study is to collect information about our community's COVID-19 exposures, symptoms, and health care visits due to the virus.
Study Topics
Learning More about the Study Drug Lepodisiran to Reduce Heart Attacks and Stroke
The purpose of this study is to learn more about the study drug lepodisiran. We want to see if the study drug can reduce problems like heart attack or stroke in adults with elevated lipoprotein (a). We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Learning More About Blood Tests to Determine if a Cancer Patient Will Respond to Treatment
Not all patients treated with immune checkpoint inhibitors respond with tumor shrinkage. Many patients have serious side effects. The purpose of this study is to develop blood tests that can help determine if patients will respond to treatment and develop side effects.
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A Study of Telehealth to Treat Children with Medical Complexity
The purpose of this study is to learn more about using telehealth visits for children with medical complexity. We want to find out if telehealth visits can improve the health of children with chronic health problems.
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Learning More About How Gut Micro-organisms Play a Role in Prostate Cancer
The purpose of this study is to find out how the gut micro-organisms may affect prostate cancer that spreads to the bone. In this study, the methods required to study these gut-bone interactions will be developed and tested.
Study Topics
Learning More About Treating Solid Tumors with SGN-EGFRd2
The purpose of this study is to find out how well the study drug, SGN-EGFRd2, works for treating solid tumor cancers. We also want to find out what side effects may be caused by the study drug.
Study Topics
Learning More About the Use of Frexalimab for Treating Relapsing Multiple Sclerosis
The purpose of this study is to see how well the study drug, frexalimab, works for treating relapsing multiple sclerosis. We also want to learn more about possible side effects of the study drug.
Study Topics
Learning More About a New Approach to Treating Ductal Carcinoma In Situ
Some ductal carcinoma in situ (breast cancer) is lower risk than others for turning into invasive cancer. The purpose of this study is to try and figure out which ductal carcinoma in situ is low risk. It's possible low-risk breast cancer can be treated with only hormone therapy pills and avoid surgery.
Study Topics
Treating Focal Onset Epilepsy with Study Drug BHV-7000
The purpose of this study is to find out how well the study drug, BHV-7000, works for treating focal seizures. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Understanding How Chemotherapy Treatment Before Surgery Impacts Recovery
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
Study Topics
A Study of Methotrexate in People with Breast, Brain, or Spinal Cord Cancer
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
Study Topics