Search Studies
Helping Improve Breast Cancer Care for Young Women
The purpose of this study is to learn more about breast cancer in younger women and help improve care in the future. Researchers will collect blood, tissue, and stool samples from women who were diagnosed with breast cancer between the ages of 18 and 45. They will look for patterns and differences to help guide future research and treatment.
Study Topics
Studying Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about the study drug Durvalumab when combined with classic chemotherapy. We want to find out if this approach is better or worse than the usual approach for your liver cancer.
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Studying the Medicine Depemokimab for COPD
The purpose of this study is to learn more about the medicine depemokimab. We want to see if this medicine can help people with COPD feel better. Volunteers in the study will get either the new medicine or a placebo and will be watched closely for changes in their health. The goal is to see if the medicine works and is safe for people with COPD.
Study Topics
Studying Two Ways to Treat Stomach Cancer
The purpose of this study is to learn more about different ways to treat stomach cancer. Our researchers want to see if giving a cancer medicine called paclitaxel directly into the belly, along with regular chemotherapy, can help lower the chance of stomach cancer growing or spreading. We will compare this new treatment to the usual care most people get for stomach cancer.
Study Topics
Using a Small Device to Track Muscle Changes in ALS
Amyotrophic Lateral Sclerosis (ALS) is a disease that slowly makes muscles weaker and harder to control, making it tough to walk, talk, or breathe. The purpose of this study is to see how a small device called the mScan can measure muscle changes in people with ALS. The device uses a tiny, painless electrical signal to check muscles. Our researchers hope this will help track ALS over time and see how well treatments work.
Study Topics
Movement Disorder Neurology Disorders Rare Disease Bones, Joints, Muscles
Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
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Comparing Two Medicines for Brain Cancer
The purpose of this study is to find out which medicine works better for people who have a type of brain cancer called glioblastoma. We will compare the medicine niraparib and temozolomide, along with radiation therapy. The goal is to see which treatment helps more and is safer.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers
Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
Study Topics
Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)
Testing the Study Drug SNDX-5613 for Patients with Newly Diagnosed Acute Myeloid Leukemia
The purpose of this study is to learn more about the study drug SNDX-5613. We want to see if adding this study drug to the usual treatment can help patients who have just been diagnosed with a type of blood cancer called acute myeloid leukemia. We want to find out how much of the drug will cause serious side effects in patients. This will help doctors find out the best amount of the drug to use in future treatments for this cancer.
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Studying the Drug SNDX-5613 for Patients with Acute Myeloid Leukemia
The study aims to learn more about the drug SNDX-5613. We want to find the best dose for patients with a blood cancer called acute myeloid leukemia. We also want to see how this drug works when used with two other drugs, daunorubicin and cytarabine.
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Studying the Medicine Remibrutinib for a Chronic Skin Condition
Hidradenitis suppurativa is a skin disease that causes painful lumps under the skin, often in areas like the armpits or groin. The purpose of this study is to see if the medicine remibrutinib can help adults with this disease. We want to see if the medicine can safely improve symptoms and improve overall health and well-being.
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Studying the Medicine CREXONT for Parkinson's Disease
The purpose of this study is to learn more about the medicine CREXONT. We want to see if this medicine is safe and useful for patients with Parkinson's disease in their daily lives.
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Studying Care Choices After Breast Cancer Surgery
The purpose of this study is to compare two different approaches to care for breast cancer after surgery. Our researchers want to find out whether closely monitoring patients after surgery works just as well as giving additional medication to prevent the cancer from returning. This study is for volunteers who had triple-negative breast cancer and showed no signs of cancer after completing chemotherapy and surgery. The results will help doctors determine the best way to care for patients in this situation.
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Studying a Medicine for Babies with Alagille Syndrome
The purpose of this study is to learn more about a medicine called Odevixibat for babies with Alagille Syndrome. We want to see if this medicine can safely help reduce itching in babies with this health condition.
Study Topics
Genetic Disorders Rare Disease Children, Infants, Teen Health
Studying a Rare Blood Condition Over Time
The purpose of this study is to learn more about a rare blood problem called plasminogen deficiency. Researchers will collect blood, urine, and health information to find out who gets symptoms and how to help them. The goal is to improve care for people with this condition.
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A Study of a Vaccine to Help Prevent C. diff
Clostridioides difficile (C. diff) is a germ that can spread from person to person. It can cause very bad diarrhea and, in serious cases, can be life threatening. This study looks at whether a new vaccine can help prevent C. diff diarrhea or make the illness less severe, reduce doctor visits, or lower the need for antibiotics in adults age 65 and older.
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Studying Blood Particles to Help Treat Cancer
The purpose of this study is to learn more about tiny particles in the blood called extracellular vesicles. By studying this, we hope to find out more about different types of cancer and how to treat them better. We will look at the blood samples from patients with similar cancers to see if we can discover new information. This could help doctors choose the best treatments for cancer patients in the future. We are looking for volunteers with urothelial, prostate, or kidney cancer. The study team will provide more information.
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Studying Radiation vs Usual Care for Cancer that Spread to Bones
The purpose of this study is to help patients who have cancer that has spread to their bones but is not causing pain yet. We want to find out if giving radiation therapy before symptoms start can help prevent problems from bone cancer. Volunteers in this study will either get the usual care or the usual care plus radiation. The goal is to see which option works better to stop bone problems like fractures or spinal cord issues.
Study Topics
Cancer Cancer: Men's Cancer Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Solid Tumor Cancer: Women's Cancer
Studying the Medicine Erdafitinib for Brain Cancers
The purpose of this study is to test the good and bad effects of the study drug, erdafitinib. We want to find out if the study drug is better or worse than other treatments for brain cancer.
Study Topics