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Studying How Genes Affect the Way Medicine Works for People
The purpose of this study is to learn more about how people's genes affect how they respond to medicine. We will collect cheek swabs or blood samples to be stored and used in future research. Information from this study may help doctors give better treatments to people in the future.
Study Topics
Healthy Volunteers Screening and Prevention Wellness and Lifestyle
Quitting Smoking and Managing Daily Challenges
The purpose of this study is to learn more about the mood, behavior and brains of people who smoke. We want to look at how daily hassles might affect how emotional distress is managed during an attempt to stop smoking. This study does not offer a treatment to stop smoking.
Study Topics
Healthy Volunteers Substance Use (Alcohol, Illegal Drugs, Tobacco)
How Myotonic Dystrophy Type 2 Affects the Brain
Myotonic dystrophy affects the muscles and other body systems. The purpose of this study is to look at the impact myotonic dystrophy type 2 has on the brain. We also want to look at brain-based symptoms like problems with thinking, memory or motivation.
Study Topics
High Blood Pressure in Children and Teenagers
The purpose of this study is to understand what causes high blood pressure in young people. We also want to learn more about how high blood pressure can cause damage to the heart and kidneys.
Study Topics
Healthy Volunteers Heart Health Children, Infants, Teen Health
How the Brain Processes Information
The purpose of this study is to look at how the human brain processes information. We want to know how the human brain responds to different stimuli, how those stimuli make you feel, and how your feelings guide your decisions.
Study Topics
How Brain Activity Relates to Your Ability to Shift Attention in Response to Images
The purpose of this study is to look at how brain activity is related to your ability to shift attention when visual cues change. You will be asked to view specified images while receiving an MRI scan.
Study Topics
Factors in Early Adulthood that May Lead to Future Lung Disease
The purpose of this study is to find out why some people develop lung disease and others do not. The study will measure your lung health now and continue to collect data from you until the end of the study.
Study Topics
Can You Help the Tooth Fairy?
The purpose of this study is to learn more about how early life exposures can affect a child's or young adult's health. These exposures can include different things such as medications and foods. This study will be done completely online. The required baby tooth and saliva samples will be sent in using prepaid envelopes.
Study Topics
Healthy Volunteers Allergies and Immunity Stomach and Intestines Children, Infants, Teen Health
How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
Study Topics
Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Learning More About the Effects of Oxytocin on the Nervous System
Oxytocin is a naturally occurring hormone. The purpose of this study is to see how oxytocin affects the nervous system. We will be looking at how pupils change after an oxytocin injection.
Study Topics
Healthy Volunteers Neurology Disorders Bones, Joints, Muscles
Learning More About Intestinal Health in Infants and Children with a New Imaging Device
The purpose of this study is to learn more about a new type of imaging device called the iThera MSOT Acuity. We want to find out how well the device works for measuring intestinal health.
Study Topics
Healthy Volunteers Stomach and Intestines Children, Infants, Teen Health
Finding Muscle Changes in Myotonic Dystrophy Patients
Myotonic dystrophy (DM) is a disease that causes muscles to weaken and waste away. The purpose of this study is to find the best ways to measure muscle weakness and changes in patients with DM using MRI scans. Understanding these changes will help plan future studies to track the disease and test new treatments. We are seeking healthy volunteers as well as volunteers who have been diagnosed with myotonic dystrophy.
Study Topics
Using Body Fat Images to Assess Health
The purpose of this study is to see if we can use medical images of fat throughout the body to assess your health status.
Study Topics
Aging Healthy Volunteers Heart Health Weight, Metabolism, Nutrition
Studying a New Way to Prevent Blood Clots During Medical Procedures
The goal of this study is to help people who need medical procedures where their blood goes outside their body, like during dialysis or heart surgery. We want to find a way to stop blood clots during these procedures. This study will help us learn how to prevent clots and make these procedures safer. We are looking for healthy volunteers, both adults and children, who are 17-70 years old and weigh over 110 pounds.
Study Topics
Learning How the Brain Shifts Attention
The purpose of this study is to learn how people move their attention when they see different things. We will use computer tasks and brain scans to see how your brain works when you pay attention to new things. The goal is to help scientists understand how attention changes in the brain.
Study Topics
Studying Oxytocin for Pain Relief from Heat
The purpose of this study is to find out if oxytocin, a natural hormone, can help reduce pain from heat when given through the nose or a vein. People will get oxytocin in two different ways and have their pain measured. The goal is to find out which way works better for pain relief.
Study Topics
Women's Health and Future Pregnancies
The goal of this study is to learn how a woman's health, including what she eats and the activities she does, affects her and her baby if she gets pregnant. We are inviting women under 40 who are overweight or obese and might become pregnant to volunteer for this study. The study team will provide more details.
Study Topics
Healthy Volunteers Weight, Metabolism, Nutrition Wellness and Lifestyle Women's Health
Studying a New Vaccine for Infants and Toddlers
The purpose of this study is to learn about a new vaccine for healthy babies and toddlers. This vaccine is made to protect against a germ called pneumococcus, which can cause serious infections. The study will help researchers see how well the vaccine works and if it causes any side effects. We are looking for volunteers with a child who is 42 to 89 days old.
Study Topics
Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Studying a New Pneumococcal Disease Vaccine Among Healthy Toddlers
Your child is being asked to join this study because they are healthy, between 12 to 15 months old, and have had 3 doses of Prevnar 20®. The study will test a new vaccine to see if it can protect against a germ that causes infections in children. The goal is to check if the vaccine is safe and helps the body make antibodies to fight the germ.
Study Topics
Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Learning More About Speech Profiles after a Stroke
The purpose of this study is to learn more about speech profiles among stroke survivors and healthy volunteers. Understanding more about speech profiles can help customize treatment.
Study Topics